SI
SI
discoversearch

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor.  We ask that you disable ad blocking while on Silicon Investor in the best interests of our community.  If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.
Strategies & Market Trends : Phase III awaiting (ie completed phase II, not yet in III)

 Public ReplyPrvt ReplyMark as Last ReadFileNext 10PreviousNext  
To: QuietWon who wrote ()1/30/1999 4:18:00 PM
From: QuietWon  Read Replies (3) of 32
 
IMCL - it's head & neck cancer drug C225 (co also has lung cancer - in phase 3 already - and does stem cell work)

A. Stage of Development - of furthest along product ie. AVAILABILITY criteria
- actually BEC2 drug for Lung Cancer in phase III.
- Head & neck cancer - awaiting phase III - only thing needed is approval on the protocol - clinical test portion APPROVED ALREADY by FDA

biz.yahoo.com

B. Efficacy - extent of how well treatment works (both co's work better than chemo, no probs there)

- 100% had greater then 50% regression. Included in that, 88% had complete regression
- zero, nada, nil got worse

Based on availability and efficacy, if you had cancer, which drug would you want administered?

C. Rate of regression ie. how fast tumours diminish

imcl - within 30 days, tumours are gone/unnoticeable ! I can only imagine, from my aunt who passed away in the early 1980s, and who won beauty pageants in the 1950s, how good it would feel to not have any visible tumours. If you attend an IMCL presentation, you will see before/after pictures - these will not be made available to the public without a presentation.

D. Ownership, Partners, Financial Mgmt, Insider activity

- Mgmt owns over 10% of the stock. -

- Merck Gmbh providing initial financing, milestone payments (in form of purchase of stock up to 20% of shares, at premium to then current market price). $90 million on financing in total. One of toughest things biotech co's face is financing - IMCL has it.

biz.yahoo.com

With a burn rate of 1.5m/month, IMCL has funds to last about 48 months (4 years)!

- Insider activity recently: late Nov, Chairman exercises 10,000 options @ ~$8 incurring tax liab in 1998; in Dec, a Director exercises 7,400 shrs ~$8.75 to 9, again incurring a tax liability in 1998. One Director bot at 10 3/8 -1/2 ! On Jan 26, 1999, 5,000 shares bot by a Director -> at $10 + !!

E. Biotech Stock Price Movement - statistically shown, and quoted in biz/newsweek in Dec. section on biotechs, that:

50% of longer term biotech stock price run up occurs during the period from approval to enter phase III until time of marketing approval. IMCL awaiting approval to enter phase III - medical/testing part done, just waiting for the ok on the protocol / business plan, if you will. IMCL's own press release says to happen in 99Q1

Some will take the pop on attainment approval of Phase III, but they will miss a significant rise if they don't get back in. Look at IDPH

F. Company PR (public relations)

The company likes to make announcements having significant meaning to their operations. They have not, certainly in the recent past, put out press releases about speaking at industry wide & analyst conferences. I am speaking to the company about this aspect.

For example, IMCL presented at the Hambrecht & Quist health care conference in mid January. Over 250 companies were there over 4 days. I believe that not all companies presented, further distinguishing IMCL. IMCL is the leader in its area!

On February 11-13, IMCL will present at the Cruttenden Roth 11th annual Growth Conference. phone 800-678-9147. This conference is for institutional investors.
Report TOU ViolationShare This Post
 Public ReplyPrvt ReplyMark as Last ReadFileNext 10PreviousNext