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Biotech / Medical : Lidak Pharm. [LDAKA]

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To: James Silverman who wrote (77)2/3/1997 10:01:00 PM
From: John Zwiener   of 1115
 
James, a little sensitive today? Did I mention gilead? Did I say they were wasting their time? Did I put down antisense tech? Did you read what I said? Do you really think the FDA will let antisense be used to treat herpes in otherwise heathy patients without letting some time go by to look for hidden long term side effect? Since many people who have herpes are young, what about teratogenic effects.

Antisense is a very powerful potential technology and I have previously stated it may be the biggest thing since penicillin. By the way, I have stakes in GILD,HYBN, and ISIP. I think that real treatments for cancer, viruses, fungi, parasites, aging, autoimmune diseases, and just about anything is possible with antisense. Will it work? I think so, but we still have a way to go. I also said that I thought that antisense would eventually be a better treatment for herpes than lidakol. But a healthy person who will get better anyway from herpes whether or not you treat deserves caution when a drug is promoted. Lidakol does not mess with DNA or RNA so the level of caution will not be as high. Remember acyclivir? Many docs and patients were reluctant to take it because of the fundimental level at which that drug acts. Approval for that convenience indication took a very long time.

Are you sure yourself?
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