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Gold/Mining/Energy : IGT Pharma (V.IGT) Anti-Cancer Blockbuster!!
IGT 16.66+0.4%Oct 31 9:30 AM EST
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To: Stephen O who wrote (55)2/4/1999 1:04:00 AM
From: Pawl  Read Replies (1) of 86
 
News
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IGT Pharma neurological drug development progressing

IGT Pharma Inc IGT
Shares issued 8,819,820 Feb 2 close $0.82
Wed 3 Feb 99 News Release
Mr. Bruce Schmidt reports
The company has received positive preliminary results from testing performed at the Royal Danish School of Pharmacy, Copenhagen. The objective of the testing was to provide data relating to the performance of IGT's new series of specialized amino acid type compounds on certain brain receptors. Specifically, drugs which interact with a new class of receptor called the metabotropic glutamate receptors (mGluRs) now represent the leading edge of
neurological drug development. The mGluRs may provide medical science with a better way of treating a range of neurological conditions including stroke, epilepsy, anxiety, movement control and drug dependence. The advantage of mGluRs is that certain receptor types tend to be associated with certain disorders thus allowing for highly targeted treatments with only limited side effects.
Preliminary data resulting from the study show that IGT's first series of compounds referenced as IGT440101 are specifically active as blockers of the mGluR 1 receptor. This receptor has been identified as controlling the levels of excitability of brain cells (neurons) which is implicated in conditions such as stroke and epilepsy. With these findings, IGT is now proceeding to expand its testing into animal models in preparation for a decision to enter human clinical trials. IGT's strategy will be to develop these, as well as other neurological drugs, with pharmaceutical partners with existing marketing channels. To that end, discussions are under way which may lead to meaningful longer term relationships with multinational pharmaceutical organizations engaged in the neurological treatment markets.
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