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Biotech / Medical : Ligand (LGND) Breakout!
LGND 206.36+1.4%Nov 26 3:59 PM EST

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To: Machaon who wrote (27970)2/7/1999 12:40:00 PM
From: Henry Niman  Read Replies (1) of 32384
 
Bob, the situation may be somewhat analogous to breast cancer treatment with Tamoxifen. The rationale behind the development of Tamoxifen was the observation that it acted like an anti-estrogen. It would bind to the estrogen receptor (ER) and block estrogen binding. Consequently, it was initially tested and approved for the treatment of ER+ breast cancer. However, it was subsequently observed to have an effect on ER- breast cancer also, and is now approved for the treatment of ER+ and ER- breast cancer.
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