Sepracor-Looks very promising Message Board

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Biotech / Medical : Sepracor-Looks very promising

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To: j_fir2 who wrote (1845)	2/25/1999 8:24:00 PM
From: Biomaven	of 10280

I agree that other companies are most certainly patenting the chiral versions of any new compounds they come up with, and/or looking very closely at the active metabolites. Everyone expected the SEPR strategy to be transient - the amazing thing is just how long it has lasted, with new and significant ICE patents still being granted to SEPR. The Forbes guy seemed to be saying something different. He might possibly be referring to other ways of extending the life - e.g., by combining the original with some other drug to produce a combination. Not something I'm going to lose sleep over. I agree with your other point about the ICE's. Prozac II will ultimately have to compete with generic Prozac, and this will certainly hurt it price-wise. I suspect we will see SGP and Lilly trying to switch people to Claritin II and Prozac II while their original patents are still in force - that way the improved version doesn't have to compete on price at the beginning. Your point is why I don't expect Prozac II to be a $3 billion drug. Of course, a lot will depend on just how much better Prozac II is than Prozac I. Peter

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