Ligand (LGND) Breakout! Message Board

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Biotech / Medical : Ligand (LGND) Breakout!

LGND 203.64

+2.3%

12:39 PM EST

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To: Henry Niman who wrote (28444)	3/2/1999 9:55:00 AM
From: Mudcat	Read Replies (1) of 32384

I was under the impression that in the rat models, Targretin produced results that were better than the results produced by Tamoxifen in rat models. If this is the case, then why would you use a combo of Targretin and Tamoxifen if Targretin alone would destroy the tumors? Are they only using a combo in tests now because Tamoxifen is approved and people may not want to die testing an unproven drug alone. Do SERMs only compete with SERMs or will the SERMs compete with Targretin if the rat results are confirmed in humans?

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