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Biotech / Medical : XOMA. Bull or Bear?
XOMA 24.99+1.5%Jan 29 3:59 PM EST

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To: Chris Boylan who wrote (8986)3/8/1999 4:14:00 PM
From: xomadog2  Read Replies (1) of 17367
 
Dear Chris Boylan:

I do not agree with your comments regarding the trial in phase 3 meningococcemia. It is not correct that the trial is being extended for a second time!!!!

The only time that the trial was extended was at the sugeestion of the DSMB in September,after the last interim analysis.

It is also not possible for you to have reason to believe that the company does not have statisically sufficient results to stop the trial. THE ISSUE FOR THE COMPANY to end the trial IS NOT STATISICALLY SUFFICIENT RESULTS.They are in need of having enough mortality(deaths) occur in the trial. This is not related to the efficacy hurdle that will be looked at after the number of minimum events is achieved in this trial.
Please keep in mind that the assuming they have reached the minimum number of events and assuming that they decide based on the DSMB advice to end the trial..The data will stay unblinded until the follow up is done and the company is ready to unblind the data.

There is also another phase 3 coming to completion in Trauma for the same drug. There is also,another possibility,source, of financing.
GNE might be seriously enough interested in continuing the HU1124
trials that they fund the money upfront and enbale XOMA to have some
money in the till.All the tools are around to buy time to get to the end of the meningococcemia trial,the trauma trial and ,see what the results for Neuprex are. If the results are positive, XOMA will have no problem arranging for new money.
Yes, in a way this islike wildcat oil drilling.If you cant take the heat you always can sell or stay short. GOOD luck.
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