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Biotech / Medical : XOMA. Bull or Bear?
XOMA 25.66+2.8%Jan 30 9:30 AM EST
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To: Bluegreen who wrote (9024)3/9/1999 1:04:00 PM
From: Webhead  Read Replies (1) of 17367
 
Hey lighten up BG! Just because someone isn't spouting the party line on this board don't jump on them and suggest hidden agendas. I too am worried that the trial just keeps on going and going and going. My perhaps mistaken understanding of the DSMB function is that they only stop a trial if safety concerns arise or there is a terriffic response rate. If (God forbid) BPI isn't reducing mortality relative to the placebo group then in the absence of safety issues the DSMB would not stop the trial. From the limited data we have I can only conclude that overall mortality is much lower than expected and that BPI can't be working great (like in the PII) or the trial would have already stopped. This is not to say that BPI won't be approved or offer a tremendous theraputic advantage but we have to stop relying on the PII results as an indication of efficacy since if BPI were still working that well the trial would have already been stopped.

BTW BG, I've been long Xoma for a few years so don't waste your time trying to dismiss my justifiable concerns by claiming that I have some hidden agenda. Besides, with my broker (and I'ld assume for the vast majority of people who read this board) you can't even short a stock as low as Xoma is now.

Ed
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