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Biotech / Medical : XOMA. Bull or Bear?
XOMA 25.710.0%Jan 27 3:59 PM EST
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To: Robert K. who wrote (9119)3/11/1999 1:11:00 PM
From: aknahow  Read Replies (1) of 17367
 
"There were over 2500 cases and 246 deaths in 19973 and the disease
has an overall mortality of about 10%" Again a bit over 50% were just meningitis, and not related to the present trials. Question did the U.K. suddenly from 1997 to 1999 change the standard of care so much that the death rate declined greatly? No.

If the overall death rate is 10% what was it for just meningococcal sepsis? Higher?

In the absence of data showing how many cases and how many deaths for meningococcal sepsis I would discount any puff pieces. I think Cacaito is correct, in letting us know that this is a tough disease and carries with it a high mortality. Now with 370 patients in the trials at 20% we would have seen 74 patients no longer living if Neuprex was not working. We would have seen the trial halted for futility. And we would probably have reached the target established when the trial began with expectations of 200 enrollment. Even Bluegreen would not have dreamed up 74 non living as a reasonable target out of 200.

Again, I think the market is starting to see what we have debated and have had difficulty seeing. Extension of the trial and failure to achieve a non survival rate are probably bullish events. With full confidence i predict that when the market figures out what Opalapril means we will really see what can happen. <VBG> Disregard the VBG. IMO a <g> is sufficient except for Bob.
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