I trust Wisconsin. When mortality measured by severity, results did not change. Also if resistance is in any way a concer on might postulate that fewer non survivors might exist as time moves on. (my idea not that of the real dudes that wrote the article).
Pediatr Infect Dis J 1989 Jan;8(1):8-11
Trends in mortality in children hospitalized with meningococcal
infections, 1957 to 1987.
Havens PL, Garland JS, Brook MM, Dewitz BA, Stremski ES, Troshynski TJ
Department of Pediatrics, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee 53201.
We reviewed charts of 261 children seen at Children's Hospital of Wisconsin from 1957 to 1987 with culture-proven
meningococcemia or meningococcal meningitis, and we analyzed trends in mortality and disease severity for that interval.
Overall case fatality was 10%, ranging from 9% in the period 1957 to 1963, to 16% in the period 1980 to 1987 (P =
0.15). The percent of patients admitted with severe disease increased from 14% to 38% (P = 0.001). When stratified by
disease severity, case-fatality rates did not change with time. We conclude that technologic advances of the past 30 years
had no measurable impact on mortality from meningococcal infection in our hospital and that crude case-fatality rates can
be misleading if disease severity is not considered.
MeSH Terms:
Me again, so over 30 years there was no change in the survival rates in Wisconsin, a great state, with some of the cleanest hospitals that exist anywhere, but in the u.k. from 1997 to 1998 there was this big increase in survivorship! Give me a break!
Did the regular posters not survive some event, called Friday? Or the release of the S3. did I alone survive some clinical trial that will never end because of a pre established target that was too high? |
