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Biotech / Medical : VVUS: VIVUS INC. (NASDAQ)
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To: DaiS who wrote (19769)3/14/1999 7:48:00 PM
From: Zebra 365  Read Replies (2) of 23519
 
BigKNY was transiently a VVUS investor (10 to 14 and out as I recall) but mostly sticks to Big Pharma, however he is also somewhat of a TA player and the TA on VVUS is looking better than it has in six months. I suspect he also hangs around this board because of the level of discussion. He is not an MD but has at least one sibling who is.

"It would seem that Drs Kaplan and Berman would be as one in accepting that viagra causes increased blood flow to the female genitalia. But they are concerned with whether or this translates into increased sexual satisfaction?"

DaiS,

This is a big question. I used to joke that Dr. Goldstein thought that you make a dog happy by moving its tail back and forth. There are several forms of sexual dysfuction in women, anorgasmia, dysparunia, and decreased libido are probably the majors.

Testosterone is a major driver of libido for men and women. Women who have persistent vasomotor symptoms on estrogen alone may be given a small amount of testosterone as in Estra-Test. I have used this also with some success in women who complain of decreased libido or anorgasmia on SSRI's (if they are already on an estrogen supplement.)

Whether local changes in pelvic blood flow will affect a problem whose source is probably nearer the hippocampus, remains to be seen. Also I think alprostadil would be a poor choice for this use in women as there is a great risk of inducing spontaneous abortion using prostaglandins in women who are pregnant. However, alprostadil is generic and not patented by VVUS, many other safer vasodilators would be available for use under this patent.

Zebra
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