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Biotech / Medical : XOMA. Bull or Bear?
XOMA 26.15-0.7%Jan 20 3:59 PM EST

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To: Cacaito who wrote (9302)3/20/1999 9:01:00 PM
From: aknahow  Read Replies (2) of 17367
 
Cacaito, this must have disturbed you greatly because I now not that after teaching me to say arms, rather than legs, you now say legs. <g>

Original accruals contemplated were 200.

Placebo 80% in less severe. Mortality 20% = 16
Placebo 20% in more severe. Mortality 30% = 6
. ......... ......................... = 22

Treatment 80% in less severe. Deaths 10% = 8
20% in more severe Deaths 15% = 3
......................................... = 11

Total assumed mortality at start of trial 33

Obviously many other conclusions could be reached. I have no knowledge of any facts that would permit an accurate calculation. I post in part because shareholders were deprived of crucial information in theory to keep them from speculating on the above. This was unfair and not something the DSMB should have done. The actions of the DSMB created greater uncertainty and did not help to strengthen XOMA financially.

If there is a next time I hope XOMA will be stronger and not let a DSMB intrude into a this type of decision.
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