Maybe it was ARIS ...not ARIAD...the one that was sponsored by Cowens...it was in that 1996 Biotech Book. They sponsered that IPO I was referring. LOOK: Maybe this is why ARAID stuck in my mind: Pangea Systems Tools Used to Design DNA Expression Chips for Hoechst Marion Roussel
Business Wire - February 02, 1999 08:21
OAKLAND, Calif.--(BW HealthWire)--Feb. 2, 1999--Pangea Systems, Inc. announced today that its computational tools are being used by Hoechst Marion Roussel and the Hoechst-ARIAD Genomics Center (a joint venture of Hoechst Marion Roussel and ARIAD Pharmaceuticals) to efficiently and accurately design custom gene expression chips from full length gene sequences and clustered gene fragments, called expressed sequence tags (ESTs), identified by Hoechst Marion Roussel.
The new chips will enable Hoechst Marion Roussel to study gene families of potential therapeutic interest and validate their usefulness as drug targets.
"Pangea's software is particularly valuable because it allows us to automatically integrate information from our compiled internal databases into designs for the manufacture of gene expression chips," said Rich Hamer, Ph.D., head of Hoechst Marion Roussel's Global Bioinformatics Group. "With the help of Pangea's tools, we were able to significantly accelerate our internal chip design process."
"This relationship between Pangea and Hoechst Marion Roussel further validates our chip design software, and illustrates how Pangea is closing the gap between genome sequencing efforts and drug target validation," said John Couch, chief executive officer of Pangea Systems, Inc. He noted that the Hoechst-ARIAD Genomics Center had previously licensed Pangea's EST Clustering and Alignment tools for use in the company's bioinformatics programs.
Pangea's chip design tools uniquely automate the identification and selection of gene sequences for incorporation in custom DNA expression chips, rapidly producing error-free sequence sets in the appropriate format for chip manufacture. As a result, sequence selection and chip design efforts that previously required weeks to months of hand labor can be accomplished automatically in hours with greatly improved accuracy.
"Pangea's chip design software amplifies the gains that EST Clustering and Alignment tools provide," added Couch. "One component of the Pangea chip design tools automatically segregates and classifies gene isoforms and polymorphisms that may be linked to disease. The Pangea tools automatically identify optimal regions for chip design, and output the results into the input format developed by the leading chip manufacturer, Affymetrix."
Hoechst Marion Roussel is the pharmaceutical company of Hoechst AG. The Hoechst-ARIAD Genomics Center, a joint venture of Hoechst Marion Roussel and ARIAD Pharmaceuticals (Nasdaq:ARIA), utilizes functional genomics technologies to identify novel therapeutic targets and therapeutic proteins.
Pangea Systems, Inc. is a leading provider of software for advanced bioinformatics -- the application of information technology to life science research and development.
The company's mission is to provide pharmaceutical and biotechnology companies with operationally proven software applications, unique scientific (computational) tools, an open computing environment, and value-added professional services that integrate the collection, organization and analysis of biological and biochemical information. In doing so, Pangea's bioinformatics software simplifies and accelerates the drug discovery process in ways never before achieved.
Incorporated in 1993, Pangea Systems, Inc. is a privately held, Oakland, Calif.-based company. For more information, contact Pangea Systems, Inc. at 510/628-0100, or e-mail us at info-pr@pangeasystems.com or visit pangeasystems.com.
Note to Editors: Pangea Systems is a registered trademarks of Pangea Systems, Inc. The Pangea Systems logo, is a trademarks of Pangea Systems. Inc. All other trademarks, brands and names are property of their respective owners.
CONTACT: Pangea Systems, Inc. Marie Martin, 510/628-0100 mariem@pangeasystems.com or J. Kureczka Associates Joan Kureczka, 415/821-2413 jkureczka@aol.com Chuca |