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Biotech / Medical : COMPUTERIZED THERMAL IMAGING (COII)- research only
CIO 6.865+0.4%3:59 PM EST

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To: chirodoc who wrote (111)3/30/1999 1:16:00 AM
From: chirodoc  Read Replies (1) of 256
 
this is why PET scans are no competition for coii

note that patients were injected with 740 MBq 99Tcm-MIBI--this is the radioactive substance that is used to make things light up. do you think women want to drink this if they do not have cancer already? i doubt it. also note that the accuracy is no better than thermal imaging--in fact it looks less accurate!

Nucl Med Commun 1999 Mar;20(3):237-45

Prone SPET scintimammography.

Buscombe JR, Cwikla JB, Thakrar DS, Parbhoo SP, Hilson AJ
Department of Nuclear Medicine, Royal Free Hospital, London, UK. buscombe@rfhsm.ac.uk

[Medline record in process]

Prone single photon emission tomography (SPET) was performed in 24 patients with suspected primary or recurrent breast cancer to determine if this technique offers more accurate imaging than that obtained from planar scintimammography. All patients were imaged on a specially designed couch with two cushion inserts. The first insert was lined with lead and was used to perform prone lateral planar scintimammography 5 min after the injection of 740 MBq 99Tcm-MIBI. The second insert did not contain lead and was used to perform a prone SPET acquisition for 30 min immediately after planar imaging. The results of both studies were read independently and there was agreement between the two techniques in 23 cases (96%). All cases of cancer proven on histology were found on planar imaging, but a 4-mm ductal cancer was missed on prone SPET. This was thought to be due to activity from this medial cancer being obscured by the star artefact produced by back-projection reconstruction from activity in the heart. There were two false-positive studies with both techniques. However, prone SPET enabled better localization and characterization of breast cancers than planar imaging. Prone SPET imaging of the breast produces results similar to prone lateral imaging and may be used instead of planar imaging if a reduced total acquisition time is desirable. Care must be taken when reading scans in the presence of small tumours near the heart when back-projection reconstruction techniques are used

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