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Biotech / Medical : Biotech Derivatives

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To: scaram(o)uche who wrote (113)	4/20/1999 2:49:00 PM
From: SnowShredder	Read Replies (1) of 555

The thing to worry about with Onyx-O15 is that if this isn't true... >>defective p53 signal is required for replication<< and a defective p53 signal is not necessary then their patent protection may be in danger...since their mutant virus would b a slower replicating Ad vs. wt. So for treatment of cancer it might be more beneficial to just to use a wt Ad instead, since the faster replication will lyse the infected cells sooner...increasing the amount of viral spread & tumor shrinkage before the immune response really kicks in. Then why would it be more beneficial to use the mutant virus? (JMHO)...Best of Luck, Where'd He Go?

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