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Biotech / Medical : Sepracor-Looks very promising

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To: BMcV who wrote (2788)5/17/1999 7:45:00 AM
From: BMcV  Read Replies (3) of 10280
 
Looking more closely at the data, it looks to me like the results compared to Loratadine (Claritin) are somewhat ambiguous, making the efficacy comparable to slightly better. There were two studies, each over both 12 and 24 hours. A 30 mg dose of Nori was better than Lori in both cases, but only slightly so in the second study.

sepracor.com

Over 24 hours, Nori was quite a bit better in the first study, particularly over time:

sepracor.com

but not quite as good in the second study:

sepracor.com

Allergy studies are notoriously problematic, since the symptomology is so subjective. Lots of people report no results with popular medications, better results with placebo, etc.

Still, owning the rights to a drug that is now proven to be at least as effective as Claritin isn't a bad place to be. Glaxo keeps coming up as a possible partner, given their involvement in respiratory therapeutics and lack of an antihistamine. I wonder if some generic shop like Mylan might not be a good partner, not the least since they could be a better fit culturally.
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