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Biotech / Medical : XOMA. Bull or Bear?
XOMA 26.70-0.8%Jan 23 9:30 AM EST

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To: Cacaito who wrote (10069)5/18/1999 10:03:00 PM
From: Cacaito  Read Replies (1) of 17367
 
Sepsis activation:

ncbi.nlm.nih.gov

...model of paf activation, and notice persistency, exageration...

ncbi.nlm.nih.gov

....another model this time with gram negative....

ncbi.nlm.nih.gov

...notice how paf in normal mice activates more production of itsel intracellularly...

ncbi.nlm.nih.gov

...paf activated by gram positive debris, noticed activation of TNF, and activation of intrcellular paf well beyond the initial activation by the offending agent debris.

ncbi.nlm.nih.gov

...pure model with just paf, no bacteria...

ncbi.nlm.nih.gov

... explanation of mechanisms involved in some forms of shock and multiorgan failure due to wrong activation of immune response in cases like trauma, no bacteria involved...

Shock could go into vicious cycle of exagerated repetitive activation with or without bacteria at the start or at the end.
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