FYI, Patent granted to Duramed on June 1, 1999
United States Patent 5,908,638
Huber , et al.
June 1, 1999
Pharmaceutical compositions of conjugated estrogens and methods for their use
Abstract
This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal disorders in women. The novel pharmaceutical compositions comprise a carrier base material and conjugated estrogens formed into a solid unit dosage form possessing a regular incremental release of the medicament upon oral administration. Further, the invention
comprises the combination of conjugated estrogens with progestogens in a solid, shaped dosage unit. Specifically, the invention comprises the use of an organic excipient such as high molecular weight hydroxyalkyl alkylcelluloses. The use of an organic excipient such as hydroxypropylmethylcellulose in a stable, solid dosage formulation containing either conjugated estrogens alone or in combination with a progestogen is described.
Inventors: Huber; Harold Eugene (Cincinnati, OH); Ryan; Mary Katherine (Mainville, OH)
Assignee: Duramed Pharmaceuticals, Inc. (Cincinnati, OH)
Appl. No.: 690407
Filed: July 25, 1996
Well, all they have to do is sell it and they will have a nice market for the next 17 years.
Thure |
