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Biotech / Medical : Monsanto Co. -- Ignore unavailable to you. Want to Upgrade?


To: Dan Spillane who wrote (2151)6/8/1999 2:31:00 PM
From: Anthony Wong  Respond to of 2539
 
British Farmers Spurn Genetically Modified Crop Trials

Updated 10:27 AM ET June 8, 1999

By Paul Keller

LONDON (Reuters) - British farmers are increasingly wary
about running trials on genetically modified (GM) crops, fearing
the public might turn hostile or boycott sales of other farm
produce, farming experts said Tuesday.

"There is a high degree of concern about public opinion over
these trials (among farmers)," said Bill Shannon of the
Cooperative Wholesale Society, which farms over 80,000
acres and was one of the first farming groups to pull out of
recent GM crop trials.

Some farmers worry their image could be damaged and say
the trials to assess the environmental impact of GM crops will
do little to allay unease about so-called "Frankenstein foods."

Others fear their crops could be burned by environmental
protesters who want a ban on all GM trials on the grounds they
new crops could contaminate surrounding fields and plants.

Monday a British farmer conducting a large-scale trial bowed
to local opposition and destroyed his 25-acre trial crop of GM
oilseed rape with weedkiller.

He said he had been prompted by fears the farm might lose a
lucrative organic farming certificate for its winter beans and that
protesters might damage the crops.

Government figures Tuesday appeared to show that concern
about the public's reaction to the experiments had resulted in
fewer farms taking part in trials sponsored by bio-technology
firms compared with last year.

The drop in numbers -- falling to 146 trials this year from 170
-- was described by a government spokeswoman as "quite
understandable." It could be explained partly by
bio-technology firms having fewer crops they wanted to test,
she said.

"But it is quite understandable with all the negative publicity that
they may not be finding as many farmers who want to hold
trials," she said.

The government is holding its own trials of GM maize and
oilseed rape which are expected to last four years.

British consumers, prompted by the well-publicized concerns
of green groups and heir to the throne Prince Charles, are
nervous about GM ingredients and supermarkets have been
competing to remove them from their product lines.

The Norfolk Genetic Information Network pressure group --
based in eastern England where GM crop testing is
concentrated -- asked farmers to list their concerns about the
trials.

"There was a surprisingly wide range of concerns. We had
expected farmers involved in the trials to be quite gung-ho
about it," said spokesman Jonathan Matthews.

An overriding factor had been the perceived impact on the
marketability of crops produced on farms where GM crop
trials were taking place, he said.

Consumer hostility toward GM foods has evoked memories of
the mid-1990s when millions of shoppers shunned British beef
because of a link to Creutzfeld-Jakob disease, the human
equivalent of mad cow disease.

An ICM poll in Tuesday's Guardian newspaper showed over
40 percent of those questioned said they had no faith in what
scientists said regarding the safety of GM food.

news.excite.com



To: Dan Spillane who wrote (2151)6/8/1999 2:38:00 PM
From: Anthony Wong  Respond to of 2539
 
Getting Nostalgic About 'Nature'

In the debate over genetically modified crops, the question isn't
what's natural-it's what's right. And that's hard political work.

Oliver Morton
Newsweek International, June 14, 1999

One of the few diverting aspects of Britain's largely joyless European
election campaign has been the Natural Law Party's approach to the
issues. Other parties say simply that a particular version of Britain's
relationship with the rest of Europe would be a rather good or bad
thing-whatever. The Natural Law Party, on the other hand, promotes the
values of Transcendental Meditation and yogic flying, an advanced form of
the art which consists of flapping your knees while bouncing around in
something like the lotus position. Apparently this has already lessened
levels of violence in both Merseyside and the Middle East. The Natural
Lawyers do, however, have one concrete political policy. The party wants
a Europewide ban on all genetically modified crops.

In this, if in little else, the Natural Law Party is very much in the
mainstream. The British public has taken against genetically modified crops
in a big way. Activists uproot them and supermarkets attempt not to
furnish their customers with them. This week the Prince of Wales-a
landowner and organic farmer-came out against them for the umpteenth
time, a piece of nonnews that still managed to provoke headlines
throughout the realm.

Europeans have in general been more skeptical about genetically modified
crops than Americans, who have so far swallowed the idea, and the food,
with relatively few qualms. And among the Europeans the Brits have been
particularly adamant in their refusal to have any truck with such things. The
recent history of British agricultural politics-the culling of millions of cows
for fear that their increasing madness was spreading into the population at
large-has left the public profoundly distrustful of "unnatural" tinkering in
the food chain. The prince says that he wants us to reject all genetic
modification and instead "work with nature for the long-term benefit of
humankind."

The problem with this desire is that nature has no interest at all in the
long-term benefit of humankind. Nature has no interest in anything. And
even if it did, mankind has been overriding nature routinely for millennia.
That's what agriculture is all about. A "natural" Britain would be a
woodland that could feed only a few-when not covered by the glaciers
of a "natural" ice age. Selective breeding-a subject royalty understands in
its bones-removed nature from the farmyard long before the first
endonucleases started to cut up the first artificial strands of DNA.

People like the prince use "nature" not biologically but nostalgically, to
refer to a time when things were not so dashed artificial. This is the
perennial window dressing of the reactionary, nature as an ideological
prop for people whose notion of what is natural tends to include their own
position in society. For the prince-doubtless considered by many, if not
himself, as Britain's "natural" sovereign-nature is part of our very souls,
which is why we have an "instinctive" nervousness about tampering with it.
His love for authentic British farming practices is thus part of his sense of
what the nature of the British people is, an ideology of blood and the Soil
Association.

It is no shock that a man whose own genes have a constitutional
importance should worry about genes elsewhere. And some issues that the
prince brings up are legitimate causes for concern. The effect of genetically
altered organisms on the wider environment needs to be understood better
than it is today. The idea that this technology may be controlled by very
few companies is disturbing. It fuels widespread fear that genetic
modification will serve only as a handmaiden to agribusiness, rather than
producing higher-yielding crops to be distributed equitably among farmers
in developing countries. But these are all arguments for getting the genetic
modification of crops right, technically and politically: not for abandoning it
as intrinsically immoral simply because it is unnatural.

The question is not what is natural. It is what is right. Reaching a judgment
about that means balancing a lot of different issues and interests: the
freedom a company should have to pursue profit within the law; the fear of
harm to health or the environment; the altruistic wish to develop
technologies that genuinely help developing nations; the self-interest that
leads people to want cheaper or better food. Balancing these things is hard
political work. But it is possible, and democracies have shown themselves
in the long run to be pretty good at it. Democratic efforts to such ends,
however, are not helped by a counterproductive nostalgia. Being unhelpful
is not against the law, nor should it be. But the fact that Charles gets a
platform on such matters purely because of the situation he was born into
is still offensive. The bouncy-bottomed Natural Law Party may stand for a
lot of tosh, but at least it stands for elections. That puts it one up on the
prince.

newsweek.com:80/nw-srv/printed/int/socu/ov0624_1.htm
newsweek.com:80/nw-srv/printed/int/socu/ov0624_2.htm



To: Dan Spillane who wrote (2151)6/8/1999 2:48:00 PM
From: Anthony Wong  Respond to of 2539
 
Philippines readies Euro food ban

Updated 9:18 AM ET June 8, 1999

MANILA, Philippines, June 8 (UPI) Philippine authorities are
set to impose an import ban on certain European agricultural
products over fears of contamination by the cancer-causing
chemical dioxin, an official said.

The ban to be imposed by the agriculture department would
cover pork, poultry, eggs and related products coming from
Belgium, France, Germany and the Netherlands, said an official
of the government's National Meat Inspection Commission.

The Philippine plan is in line with moves in a growing number of
countries to ban European food imports because of fears of
dioxin contamination, which was believed to have been
introduced into the food chain through Belgian animal feed.

The commission's chairman, Edgardo Dimalanta, said any
poultry products imported before the ban takes effect will be
impounded until it is confirmed that they were not contaminated
with the chamical.

Elsewhere in Asia on Tuesday, Taiwan suspended all imports
of Belgian dairy products and animal feed effective
immediately.



To: Dan Spillane who wrote (2151)6/8/1999 4:43:00 PM
From: Anthony Wong  Read Replies (1) | Respond to of 2539
 
IMS HEALTH Reports 4,797 Prescriptions Dispensed in U.S. For Vioxx in First 10 Days of Prescription Activity
Compares to 3,231 for Searle's Celebrex over same period

Updated 3:44 PM ET June 8, 1999

LONDON (BW HealthWire) -
IMS HEALTH (NYSE:RX)
today reported that 4,797
prescriptions were dispensed in
the U.S. for Vioxx, Merck & Co.
Inc.'s Cox-2 inhibitor, in the first ten days of prescription activity.
Vioxx was approved by the FDA May 20 for relief of the signs
and symptoms of osteoarthritis, management of acute pain in
adults and treatment of menstrual pain. This prescription activity
compares to 3,231 prescriptions dispensed for Celebrex --
Searle's Cox-2 inhibitor, introduced in January 1999 -- over its
first ten days of prescription activity. IMS HEALTH is the
world's leading provider of information solutions to the
pharmaceutical and healthcare industries.

Of the Vioxx prescriptions dispensed for the week ending May
28 -- representing the first four days of prescription activity --
IMS HEALTH's National Prescription Audit Plus(tm) (NPA)
reports that 47 percent of business was generated by Primary
Care Physicians, which include Family Practice, General
Practice, Internal Medicine, and Osteopathic Medicine. More
than 29 percent of Vioxx prescriptions were dispensed by
Rheumatologists during this period.

IMS HEALTH's weekly National Prescription Audit Plus
prescription activity report, covering the Memorial Day week
ending June 4, becomes available on June 14. This report will
capture data from the first full week of Vioxx on the market and
includes mail order prescriptions.

IMS HEALTH's weekly prescription tracking service is the
most complete service of its kind covering the U.S.
pharmaceutical industry. The service provides comprehensive
coverage of three U.S. retail channels -- chain drugstores,
independent pharmacies and food stores with pharmacies -- and
includes cash and Medicaid prescriptions as well as third party
reimbursement. It also provides unique access to mail order
prescriptions.

IMS HEALTH is the world's leading provider of information
solutions to the pharmaceutical and healthcare industries. With
more than $1.2 billion in 1998 revenue, IMS HEALTH operates
in over 90 countries. IMS HEALTH is the largest
pharmaceutical manufacturer information partner, with over 40
years' experience in the industry. Key products and services
integral to customer day-to-day operations include: market
research for prescription and over-the-counter pharmaceutical
products; sales management information to optimize sales force
productivity; technology-enabled selling solutions for sales and
marketing decision making; and technology systems and
information services that support managed care organizations.
Additional information and previous press releases are available
at the IMS HEALTH website: imshealth.com.

Contact: IMS HEALTH U.S.: Nancy Duckwitz (610) 834-5338 or U.K.:
Michael Gury +44 171-393-5864

news.excite.com



To: Dan Spillane who wrote (2151)6/9/1999 10:18:00 AM
From: Anthony Wong  Read Replies (1) | Respond to of 2539
 
Merck Says Trial Shows Vioxx Better For Pain

Updated 6:41 AM ET June 9, 1999

LONDON (Reuters) - U.S.
drug group Merck & Co said
Wednesday that results of the
first head-to head trial of its new
analgesic Vioxx showed
superiority in three areas over its
major rival, Monsanto Co's Celebrex.

The company said in a statement that in trials on relief of acute
pain following dental surgery, Vioxx had faster onset of action
-- 30 minutes compared to one hour -- and "significantly
better" peak efficacy.

The company said the trial also showed that pain relief after a
single dose of Vioxx lasted 24 hours compared to five hours
for Celebrex.

A spokeswoman for Monsanto's pharmaceutical unit Searle
said the company would issue a response to the findings later
Wednesday.

Vioxx was cleared for sale in the UK on June 8, the first
European Union market to approve the product, and was
approved by the U.S. Food and Drug Administration on May
20.

IMS Health figures published Tuesday showed doctors in the
U.S. wrote 4,797 prescriptions for Vioxx in its first ten days on
sale, compared with 3,231 prescriptions for Celebrex in the
first ten days following its launch in January. Celebrex is being
co-marketed by Pfizer Inc.

Both drugs are part of a new class of pain relievers known as
Cox-2 inhibitors, which block an enzyme linked to
inflammation.

The main target market for both products, which have been
dubbed "super aspirins," is relief of pain caused by arthritis.
The great hope of Cox-2 inhibitors is that they will alleviate
much of the gastro-intestinal side effects, including ulcers,
linked to existing pain killers such as ibuprofen.

Merck said although the incidence of gastro-intestinal
complications in patients treated with Vioxx had been
minimized, "the risk has probably not been completely
eliminated."

news.excite.com



To: Dan Spillane who wrote (2151)6/10/1999 12:12:00 AM
From: Anthony Wong  Read Replies (1) | Respond to of 2539
 
Dan, this is something you've pointed out time and again, that there would be a significant price difference in food using non-GM ingredients [versus food using gm ingredients]:

Northern Foods go GM-free
itn.co.uk:80/Business/bus19990609/060902bu.htm

Lord Haskins admitted that in time GM products may again be used in the
firm's foods, if they could be proved to be safe to their customers satisfaction,
and there was a significant price difference.

He suggested that as GM soya became more and more widespread,
non-modified soya might become very expensive, while segregation of GM
soya in animal food could soon become effectively impossible.