Pfizer sheen dulls, for now, after painful setbacks
  June 18, 1999
   By Ransdell Pierson
   NEW YORK (Reuters) - Pfizer  Inc., whose profile and stock  soared last year with the launch  of impotence pill Viagra, is  nursing painful bruises after a  series of recent setbacks that hurled its share price back to  earth.
   The nation's No 2 drugmaker has been hurt by dire safety  warnings about its antibiotic Trovan, as well as the failure of  Viagra to live up to bullish sales forecasts, interest-rate worries  and other factors weighing down the whole drug group.
   New York-based Pfizer has seen its share price careen from a  lifetime high of $150 in April to Thursday's closing price of  $100.25 -- a 33 percent drop that has rubbed much of the luster  off the company's image as a powerhouse drugmaker.
   "For the year to date, Pfizer's shares are down 20 percent,  making it the worst-performing stock among major U.S.  drugmakers. It's phenomenally disappointing that this could  happen to such a high-quality company," said Brown Brothers  Harriman drug analyst Mike Krensavage.
   "People realize now the company does not walk on water," said  Krensavage, who maintains a "neutral" rating on Pfizer, even  though he expects it to post impressive per-share earnings  growth of 20 percent this year and 19 percent in 2000.
   Krensavage said that's better than the 15 percent earnings  growth expected this year and next for Pfizer's peers.
   "But Pfizer's stock is about 30 percent more expensive than the  rest of the drug group," he added, noting it's priced at about 41  times expected 1999 earnings of $2.40 per diluted share.
   On April 12, Pfizer stock hit its all-time high of $150. The stock  prices of Pfizer and other large U.S. drug companies began  falling that week as investors fled to shares of "cyclical"  companies whose prospects improve with a strengthening global  economy.
   Pfizer shares also took a pounding April 15 when the company  warned that second-quarter growth in per-share earnings would  be held to single digits, in part because of a dramatic boost in  research and development expenses.
   The company added that second-quarter comparisons also  would suffer because wholesalers stocked Viagra more heavily  in the same quarter last year, soon after its U.S. launch.
   On another negative note, Viagra's first-quarter 1998 sales of  $193 million were 18 percent less than those seen in the fourth  quarter of 1998, Pfizer said.
   ABN-Amro drug analyst James Keeney said Viagra is likely to  have 1999 global sales of $915 million, only 16 percent higher  than last year, despite its introduction this year to Japan and  many other nations.
   He predicted Viagra will achieve ultimate peak annual sales of  $1 billion to $2 billion -- only half the magnitude of some  forecasts that echoed through Wall Street in the heady days  after the blue, diamond-shaped pill's debut in May 1998.
   Keeney said Viagra revenues in most countries typically begin  strong but then taper off after pent-up demand wanes.  Moreover, many countries have curtailed availability of the pill  under government-financed insurance programs.
   Earlier Friday, Australia said it would not cover Viagra usage  under its health benefits plan. The government said it feared  coverage would lead to misuse and overuse of the drug.
   Pfizer's luck worsened June 9, when the U.S. Food and Drug  Administration urged doctors to sharply limit use of its Trovan  antibiotic after 14 cases of acute liver failure, which the agency  said were "strongly associated" with use of the drug.
   The FDA warning prompted analysts to slash their peak sales  forecasts for Trovan to about $100 million a year, from earlier  blockbuster projections of up to $1 billion.
   "Pfizer's stock has been coming down and could continue falling  because of Trovan's diminished prospects and the flattening out  of Viagra sales," Keeney said. "Who would have thought this  would happen?"
   Although Pfizer shares have been punished in recent months, the  stock price has almost doubled in the past two years -- thanks to  the company's launch of three top-selling drugs, said Banc of  America Securities analyst Len Yaffe.
   In 1997, Pfizer began co-marketing Lipitor, a  cholesterol-lowering drug developed by Warner-Lambert Co. of  Morris Plains, N.J. Pfizer is believed to keep 40 percent or more  of all profits from Lipitor, which is expected to garner sales of  $4 billion next year and peak sales of $6 billion by 2003.
   In May 1998, Pfizer introduced Viagra, and it was like a shot  heard round the world. Doctors complained of writers' cramp  amid the frenzy for Viagra prescriptions.
   Last January, Pfizer began co-marketing the hot-selling arthritis  drug Celebrex, with its developer Monsanto Co. of St. Louis.
   "Launching three such big drugs in successive years is  unprecedented in this industry," Yaffe said, adding that sales  growth of those medicines will ensure Pfizer average earnings  increases of about 18 percent over the next three to five years.
   Analysts said Pfizer is expected to introduce other fairly  important drugs in the next few years that should augment  earnings growth -- including Relpax for migraines, Tikosyn for  heart arrhythmias and inhaled insulin for diabetes.
   But Keeney cautioned that Pfizer's best-selling drug, Norvasc  for hypertension and angina, could face strong competition by  late 2000 from a promising anti-hypertension drug being  developed by Bristol-Myers Squibb Co..
   Bristol-Myers, based in New York, has said it plans to seek U.S.  approval to market its anti-hypertension medicine, Omapatrilat,  by December, and considers it the most promising drug in its  pipeline.
   At the close Friday, Pfizer stock was down $1.25 to $99.1875 in  composite New York Stock Exchange trading. Warner-Lambert  stock rose $1.1875 to $65.75, while Bristol-Myers fell 62.5 cents  to $67.375 and Monsanto slipped 56.25 cents to $41.375, also in  composite NYSE trading.    biz.yahoo.com |