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Biotech / Medical : Biotech vs. Shorts -- Ignore unavailable to you. Want to Upgrade?


To: LLCF who wrote (30)7/26/1999 8:01:00 PM
From: scaram(o)uche  Respond to of 427
 
April 21, 1999
Dear Fellow Shareholder:

Overall, it was a tumultuous time for both U.S. and international stock
markets since last year's annual report. Market performance tends to be
cyclical, and in various cycles, certain investment styles may fall in and out
of favor. The investment climate for the past year has been difficult for small
cap and value strategies. Though it has been a trying year, we did not change
our investment strategy. We believe that the current market environment is not
sustainable and does not signal the kind of fundamental change in the long-term
drivers of equity returns that would lead us to change our investment strategy
which focuses on fundamental values.

The fiscal year was an unusual one. Although historically, on average, the
stocks of smaller companies tend to outperform those of large companies, and low
price-to-earnings stocks tend to outperform high price-to-earnings stocks(1),
this past year was the exact opposite. The larger and more expensive (in terms
of price relative to earnings) a company was, the better it fared. Investment
performance for the Funds for the year ended March 31, 1999, depended
significantly on a few factors such as capitalization, trading activity and
growth versus value. Our exposure to small cap domestic and international
stocks, low turnover stocks and our value bias hurt the Funds' performance. The
one-year returns for the International Small Capitalization and Japan Funds were
slightly better than the Funds' benchmarks(2). Please see the Financial
Highlights for performance information.

In light of the current volatility in the equity markets, we think it
important for our shareholders to understand certain aspects of the risk of
investing in the Barr Rosenberg Market Neutral Fund(3). The risks can be divided
into two broad categories: the risk that arises from investing with a particular
manager (manager risk) and the risk associated with certain investment styles
(investment risk). Manager risk is simply the risk, to the investor, of placing
assets with an individual investment manager. By investing with a manager, you
are placing your trust in the firm's investment process, trading ability and a
host of other manager-specific attributes.

Investment risk refers to the portfolio investments. The stock selection
models used by AXA Rosenberg Investment Management LLC, the Funds' manager,
result in portfolios with particular style characteristics. The most notable
characteristic of the Barr Rosenberg Market Neutral Fund portfolio is the net
bias toward stocks with traditional value characteristics (lower
price-to-earnings or price-to-book ratios, for example) and away from high
trading activity stocks. These investment style biases have had a negative
impact on the Fund returns over the most recent quarters.

Market risk, which is related to investment risk, usually refers to the
relationship between a fund's portfolio and the market as a whole. The
traditional expression of that relationship is beta, which measures changes in a
fund's portfolio return in relation to changes in the return of a broad
portfolio of investments or the "market". A goal of the Barr Rosenberg Market
Neutral Fund is to build a portfolio which has a beta close to zero. This is not
to say that the portfolio isn't risky, but rather that the return variances
simply do not follow the same pattern of the "market" as a whole.

1
<PAGE> 2

A market neutral type fund is often viewed as an asset class of its own and
may be a compliment to bond, stock and real estate investing. Because market
neutral funds hold short positions, it is recommended that investors develop a
solid understanding of the risks inherent in shorting a stock. Many market
neutral managers have witnessed increased volatility in the daily value of their
portfolios over the last year. Market neutral does not mean risk neutral. Market
neutral investment strategies can lose a significant amount of principal.

During the past year, we were pleased to welcome Dwight M. Jaffee as a
Trustee to the Barr Rosenberg Series Trust. Dr. Jaffee is the Willis H. Booth
Professor of Banking and Finance at the Haas School of Business, University of
California, Berkeley.

You can obtain more information about the Funds by calling (800) 447-3332
and following the voice prompts or visiting our new web site www.brmf.com which
we expect to be operational by June 30, 1999.

We appreciate the confidence and trust you have demonstrated with your
investments in the Barr Rosenberg Mutual Funds.

Sincerely,
/s/ Richard L. Saalfeld
Richard L. Saalfeld

President & CEO
Barr Rosenberg Mutual Funds



To: LLCF who wrote (30)7/26/1999 8:10:00 PM
From: scaram(o)uche  Read Replies (2) | Respond to of 427
 
from Barr Rosenberg N-30D (whatever that is), U.S. SMALL
CAPITALIZATION SERIES, filed 6/3/99. 100 shares of GLIA??.......

DRUGS -- 2.6%
200 Agouron Pharmaceuticals,
Inc.*........................ 11,313
36,000 Aquila Biopharmaceuticals,
Inc.*........................ 74,250
9,300 Bentley Pharmaceuticals,
Inc.*........................ 14,531
71,600 Biosite Diagnostics, Inc.*..... 716,000
142,000 Cambrex Corp................... 3,141,750
74,700 Copley Pharmaceutical, Inc.*... 634,950
61,500 Diagnostic Products Corp....... 1,491,375
100 Gliatech, Inc.*................ 2,313
27,100 Medicis Pharmaceutical*........ 813,000
20,300 Medimmune, Inc.*............... 1,201,506
23,600 Millenium Pharmaceuticals,
Inc.*........................ 737,500
22,902 New Brunswick Scientific,
Inc.*........................ 106,637
20,500 PDK Labs, Inc.*................ 92,250
20,100 Quidel Corp.*.................. 40,200
149,200 Roberts Pharmaceutical
Corp.*....................... 3,095,900
29,500 Schein Pharmaceutical, Inc.*... 383,500

Peter..... is that how you found these guys, playing with the 10-K
wizard and entering Gliatech?