EntreMed, Inc. Reports Fiscal 1999 Second Quarter Results; Executives Increase Share Ownership in Recent Private Placement Business Editors/Health & Medical Writers ROCKVILLE, Md.--(BW HealthWire)--Aug. 11, 1999--EntreMed, Inc. (NASDAQ:ENMD) today reported results for its fiscal 1999 second quarter and six months ended June 30, 1999. The Company's revenues for the second quarter ended June 30, 1999 were $1,329,031, versus $1,165,485 for the comparable period one year ago. The Company reported a net loss of ($8,008,305), or ($0.61) per share, for the three months ended June 30, 1999, as compared with a net loss of ($1,812,631), or ($0.15) per share, for the same period last year. For the six months ended June 30, 1999, the Company reported revenues of $2,773,070, versus $2,320,456 for the six months ended June 30, 1998. Net loss for the first half of 1999 was ($15,157,145) or ($1.15) per share, versus ($4,924,757), or ($0.40) per share, for the first half of fiscal 1998. At June 30, 1999, the Company had cash, cash equivalents and short-term investments of $19,016,078. On July 27, 1999, the Company completed a private placement of equity securities that resulted in gross proceeds in excess of $30 million in funding for EntreMed. The callable warrants that were granted to purchasers of shares in this transaction (at a significant premium to the present share price) have the potential to further add to the Company's resources in the future. As required by the terms of the private placement, the Company has now filed a shelf registration statement with the SEC covering the resale of the common stock issued, or to be issued, in connection with the transaction. Dr. John W. Holaday, EntreMed Chairman, President and Chief Executive Officer, Dr. Joanna C. Horobin, Senior Vice President of Commercial Development, and Wendell M. Starke, Vice Chairman of the Board, elected to increase their share ownership and purchased stock worth over $1 million as part of the recent transaction. These individuals are listed in the Company's shelf registration statement as selling stockholders. Each of these executives have advised the Company that they have no present intention of selling any shares of EntreMed stock. Dr. John W. Holaday commented: "We continue to allocate the majority of our R & D spending on the development of Endostatin(TM) protein, Angiostatin(R) protein and 2-methoxyestradiol. Through our resourceful use of funds, in less than three years we have been able to take Endostatin(TM) protein from its discovery in 1996 to commencement of human clinical trials this Fall. Additionally, we anticipate IND filings for Phase I clinical studies of Angiostatin(R) protein and 2-methoxyestradiol in the fourth quarter of this year." Dr. Holaday continued, "The rapid development of our lead product candidates and the significant progress of our Internal Discovery Program reflect the exceptional efforts of our research and development team. With efforts that began over six years ago, EntreMed scientists continue to lead critical research in the field of angiogenesis inhibition as we expand knowledge of the fundamental biological mechanisms of angiogenesis and discover new molecules. I look forward to the peer-reviewed publication of our most recent findings in the near future." R. Nelson Campbell, EntreMed's Chief Financial Officer, commented on the Company's second quarter losses: "The increased expenditures during the second quarter primarily reflect the cost of production and vialing of clinical grade Endostatin(TM) protein and production of Angiostatin(R) protein through our contract facility at Covance Biotechnology Services, Inc.. Completion of our private placement will significantly increase our resources as we initiate the clinical development of our lead antiangiogenic molecules." Rockville, MD-based EntreMed, Inc. The Angiogenesis Company (TM), is a leader in the field of antiangiogenesis research, which studies the inhibition of abnormal blood vessel growth recently associated with a broad range of diseases. The Company's strategy is to accelerate development of its core technologies through collaborations and sponsored research programs with university medical departments, research companies and government laboratories. For further information, please visit the EntreMed web site at www.entremed.com. Statements herein that are not descriptions of historical facts are forward-looking and subject to risk and uncertainties. Actual results could differ materially from those currently anticipated due to a number of factors, including those set forth in the Company's Securities and Exchange Commission filings under "Risk Factors," including risks relating to the early stage of products under development; uncertainties relating to clinical trials; dependence on third parties; future capital needs; and risks relating to the commercialization, if any, of the Company's proposed products (such as marketing, safety, regulatory, patent, product liability, supply, competition and other risks). The securities subject to the registration statement may not be sold by the selling stockholders, nor may offers to buy be accepted, prior to the time that the registration statement is declared effective by the SEC. This press release does not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state. -0- *T ENTREMED, INC. SUMMARY OF OPERATING RESULTS Three Months Ended June 30, 1999 1998 -------- -------- Total revenues $ 1,329,031 $ 1,165,485 Research & development 7,619,140 2,345,299 General & administrative 2,003,069 1,221,010 Net loss $(8,008,305) $(1,812,631) Net loss per share $ (0.61) $ (0.15) (basic and diluted) Weighted average number of shares outstanding (basic and diluted) 13,165,522 12,437,363 Six Months Ended June 30, 1999 1998 --------- -------- Total revenues $ 2,773,070 $ 2,320,456 Research & development 14,726,595 5,844,730 General & administrative 3,898,907 2,526,900 Net loss $(15,157,145) $(4,924,757) Net loss per share $ (1.15) $ (0.40) (basic and diluted) Weighted average number of shares outstanding (basic and diluted) 13,144,832 12,369,153 |