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Non-Tech : Bill Wexler's Dog Pound -- Ignore unavailable to you. Want to Upgrade?

To: Jim Roof who wrote (2890)	8/6/1999 8:00:00 AM
From: Bill Wexler	Respond to of 10293

You Biocrime shills are going to end up giving me a lot of money for the third time in a row. Unbelievable. It's rare that I see the same victims coming back again and again to get punished by the same stock. Another fine example of ego overwhelming common sense. I reiterate my STRONG SELL/SHORT SELL recommendation. techstocks.com

To: Jim Roof who wrote (2890)	8/6/1999 11:35:00 AM
From: BDR	Read Replies (1) \| Respond to of 10293

A volume expander such as Biotime's product can prevent circulatory collapse in the event of blood loss by maintaining pressure within the system. Blood has that function, too, but has the additional important function of carrying oxygen to tissues. Biotime's product and other starch solutions have about the same O2 carrying capacity as a saline solution. That is, essentially none and that is why they can only replace a portion of the total blood volume that way. If blood loss is great enough you eventually have to resort to transfusion. If we replaced your entire blood volume with something that met your definition of a blood substitute you would be dead within a matter of minutes. A synthetic blood substitute would have to have the ability to transport oxygen in order to be labeled as such. Biotime's product is a volume expander which seems to offer little advantage over other similar products already on the market.

To: Jim Roof who wrote (2890)	8/6/1999 11:44:00 AM
From: Marconi	Read Replies (1) \| Respond to of 10293

Hello Mr. Roof: BTIM simplified A volume extender replaces fluid volume presumably lost through bleeding, and is expected to help maintain blood pressure; thereby, circulation and perfusion. A blood substitute is primarily expected to transport oxygen to the tissues (and carbon dioxide from the tissues). Other blood-like properties would be desirable but have not been addressed as much as respiration has for blood substitute candidate materials. Blood is not given for efforts to maintain pressure. Blood is transfused for its living tissue qualities for which there is no substitute; oxygenation, clotting, white blood cells, etc. A volume extender replaces water lost through hydraulic loss (bleeding) or shock (fluid going from the vascular system into the intra- and extracellular volumes [outside the vascular system, but within the non-vascular tissues]). The last I heard on blood substitutes some years ago was that although they looked promising in laboratory testing, they seemed to kill patients in unexpected ways and that impasse has remained the last decade. In vitro and critter testing did not smoothly extend into the clinical setting. Blood is a vital tissue, and as stated by the Creator in Deuteronomy, 'the life of every creature is in its blood'. In contrast, a volume extender is a compatible solvent for blood, but is not alive as is the blood tissue. Regards, m