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Biotech / Medical : CLTR COULTER PHARMACEUTICAL -- Ignore unavailable to you. Want to Upgrade?

To: Bharat H. Barai who wrote (288)	8/31/1999 12:55:00 AM
From: Ben Wa	Respond to of 666

Hey umm I was just thinking that whoever is making that um...whaddayacallit...Re - toochis - an...couldn't they work on something like a next big thing too, like I mean do you think they might be working on something which would have benefited from this little teeny weeny hiccup that Coulter had today? Or maybe...is it Idec (what a funny name, huh?) figured that they had the holy grail and stopped working on anything else, right? Ya know, I've never been a compensated doctor that worked on a clinical trial. What's it like?

To: Bharat H. Barai who wrote (288)	8/31/1999 1:20:00 AM
From: Vector1	Read Replies (2) \| Respond to of 666

Dr. Barai, Thanks for the most informative post. Interesting comment on Gemcitabine. How Lilly ever got that through the FDA I will never know. I guess they will approve almost anything for Pancreatic Cancer. You are quite right on off label usage. It is a classic strategy of major pharma in the oncology area to get a drug approved for a niche indication and then conduct additonal trials and have articles published to sell off label. A company's right to use published articles has been enforced by the courts. Any thoughts on how well Bexxar will work in combination with Fludarabine. Pre-clinical studies showed synergy and CLTR is presenting on the trial in December at ASH. The trial is being conducted at Cornell Medical Center in NY. IMO once Bexxar is approved the treatment options for first line patients will be (i)Rituxan plus CHOP (ii)Bexxar(iii)Bexxar plus Fludarabine. V1