To: David Culver who wrote (67 ) 10/1/1999 1:36:00 AM From: Spiney Respond to of 94
IGT Pharma presents to international meeting on brain receptor technology IGT Pharma Inc IGT Shares issued 8,819,820 Sep 29 close $0.80 Thu 30 Sept 99 News Release Mr. Bruce Schmidt reports Results of recent advances in IGT's neurological drug development programs were presented on September 22 to the third international meeting on metabotropic glutamate receptors held in Sicily. The purpose of the meeting was to bring together scientists from leading academic, biotech and pharmaceutical organizations to report on leading-edge research relating to the use of metabotropic glutamate receptor technology in the treatment of neurological disorders. The mGluRs are now widely accepted as being the basis for a new generation of neurological drugs promising to treat neurological dysfunction more effectively and specifically than currently available treatments. Dr. Ken Curry, IGT's vice-president of research and development, presented various aspects of IGT's neuroprotective drug program, including data relating to the ability of the new drug, IGT 440103, to protect rodent brain cells from damage related to oxygen deprivation, a condition related to human stroke. Initial partnering and collaboration discussions were initiated during the meeting that may lead to expanded relationships with academic institutions and pharmaceutical organizations wishing to use IGT's technology. IGT and Dr. Curry have been acknowledged as leaders in the discovery of novel amino acids that efficiently interact with the mGluR system. IGT has recently patented five broad classes of rationally synthesized amino acids that may represent new possibilities in the treatment of stroke, epilepsy, as well as psychiatric conditions such as schizophrenia and anxiety.