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Biotech / Medical : PFE (Pfizer) How high will it go? -- Ignore unavailable to you. Want to Upgrade?


To: Anthony Wong who wrote (8216)9/23/1999 12:34:00 AM
From: Brander  Read Replies (2) | Respond to of 9523
 
Viagra Helps Impotence and Depression

When erectile dysfunction is accompanied by mild-to-moderate depression, sildenafil may improve both conditions.

Erectile dysfunction and depression frequently coexist, and it is often unclear which condition precedes the other, Dr. Matthew Menza noted at the annual meeting of the Society of General Internal Medicine.

He and his associates diagnosed untreated depression in 136 men (mean age, 56 years) who presented with erectile dysfunction to urologists.

The patients had had erectile dysfunction for an average of almost 6 years, reported Dr. Menza, a psychiatrist at the Robert Wood Johnson Medical School, Piscataway, N.J.

At baseline, the majority of patients had either mild or moderate depression, based on an average score of 17 on the Hamilton Depression rating scale.

Patients were then randomized to receive either placebo or 25-100 mg of sildenafil (Viagra), with the dose depending on efficacy and tolerability.

During 12 weeks of treatment, erectile dysfunction significantly improved in 48 of 66 men in the sildenafil group and in 10 of 70 patients in the placebo group.

Ther average Hamilton Depression rating scale score also significantly improved to a mean of 6 among the 58 men whose erectile dysfunction had responded to treatment. It did not change markedly among the men who continued to have erectile dysfunction.

--Barbara Baker--