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Microcap & Penny Stocks : Computerized Thermal Imaging CIO (formerly COII) -- Ignore unavailable to you. Want to Upgrade?

To: Dr. Bob who wrote (3620)	10/21/1999 1:06:00 AM
From: chirodoc	Read Replies (1) \| Respond to of 6039

dr. bob, if a woman has a suspicious lump, she is followed more regularly. this includes mammos and ultrasound primarily. then, a biopsy if the suspicion becomes more serious. after a woman has had breast surgery and/or chemo/radiation, she is also followed MORE closely with mammo and US whenever there is the slightest change in her condition in a more worrisome direction. although mammo is the screening of choice, it is being used in the "management" post breast cancer therapy--i am sure you know this. i am also sure that you know that US is being used in this regard as well. assuming that a cti scan will NOT become part of this trio is a guess on your part as well. i believe that cti will be part of this process and, like mammo and US will be used whenever the physician needs more information, before or after therapy. curtis

To: Dr. Bob who wrote (3620)	10/21/1999 10:47:00 AM
From: chirodoc	Read Replies (1) \| Respond to of 6039

an example of how mri/thermal are being used..... in the area of real time patient "management." 1 : J Magn Reson Imaging 1999 Oct;10(4):545-9 Related Articles MR-guided laser thermoablation of inoperable renal tumors in an open-configuration interventional MR scanner: preliminary clinical experience in three cases. de Jode MG, Vale JA, Gedroyc WM Interventional Magnetic Resonance Unit, St. Mary's Hospital, London W2 1NY, United Kingdom. [Medline record in process] A minimally invasive technique for performing magnetic resonance (MR)-guided laser interstitial thermoablation (LITT) for inoperable renal tumors is described. Three patients were treated using a percutaneous technique with real-time MR guidance in an open access interventional MR scanner. Laser therapy was delivered using a neodymium-YAG source via a water-cooled applicator system. Thermal lesions were monitored in real time using a color thermometry sequence. All patients were discharged the following day with no complications. Follow-up with gadolinium-enhanced MRI in a conventional high-field system confirmed necrosis in targeted tissue, and further treatment is planned for one patient. We concluded that LITT can be useful in treating inoperable renal malignancy and merits further evaluation. J. Magn. Reson. Imaging 1999;10:545-549. Copyright 1999 Wiley-Liss, Inc

To: Dr. Bob who wrote (3620)	10/21/1999 10:56:00 AM
From: chirodoc	Respond to of 6039

another example of how temperature is deemed important in ......patient management. Breast Cancer Res Treat 1999 Jan;53(2):185-92 Related Articles Effect of thermal variables on human breast cancer in cryosurgery. Rui J, Tatsutani KN, Dahiya R, Rubinsky B Department of Mechanical Engineering, University of California, Berkeley 94720, USA. There is a growing interest in the use of cryosurgery to treat breast cancer, following recent breakthroughs in noninvasive imaging and in cryotechnology, as well as the recent success of cryosurgery in treating various types of cancer. However, since haphazard freezing does not guarantee tissue destruction, in order to apply this technique effectively it is essential to determine the thermal parameters that produce complete destruction of malignant tissue. This study seeks to quantitatively identify the relationship between thermal variables and the degree of freezing damage to human breast cancer cells. In order to do this, human breast cancer and normal cells were frozen with controlled thermal parameters using a directional solidification apparatus. Cell viability was determined after thawing using trypan blue, and correlated to the thermal variables used during freezing. Cellular damage is observed to increase with increasing cooling rates, due to the higher probability of intracellular ice formation. A double freeze thaw cycle significantly increases the extent of cell damage, and is sufficient to ensure complete cell destruction at final freezing temperatures of -40 degrees C for a 25 degrees C/min cooling rate, and -20 degrees C for a 50 degrees C/min cooling rate. The correlations between cell death and thermal parameters are qualitatively identical for all the cell types in this study, although there is some variation from one cell type to another in the overall susceptibility to freezing damage. The correlations established in this study can be used to design systematic and optimal breast cryosurgery protocols

To: Dr. Bob who wrote (3620)	10/21/1999 11:02:00 AM
From: chirodoc	Respond to of 6039

"thermovisual definition of therapeutic targets in cases of vulvar and cervical lesions" one last example of how researchers...... are investigating using thermal imaging to assess to possiblity of therapy necessary. : Ginekol Pol 1998 Dec;69(12):1268-72 Related Articles [Infrared thermographic imaging of normal vulva and uterine cervix: a preliminary report]. [Article in Polish] Sikorski R, Smaga A, Paszkowski T, Walczak R Kliniki Ginekologii II Katedry Poloznictwa i Chorob Kobiecych Wydzialu Lekarskiego AM w Lublinie. OBJECTIVES: To evaluate in the standardized conditions the thermal emission by normal uterine cervix and vulva. MATERIALS AND METHODS: Infrared telethermography (ITT) was used to examine vulva and uterine cervix in 32 women aged 24-54 years without colposcopic and cytologic abnormalities. RESULTS: The measured temperatures differed between different topographic points of vulva and uterine vaginal portio. The inter-individual variability of temperatures determined at the same vulvar structures was relatively low. CONCLUSION: The obtained results constitute a basis for further studies on thermovisual definition of therapeutic targets in cases of vulvar and cervical lesions