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Biotech / Medical : VD's Model Portfolio & Discussion Thread -- Ignore unavailable to you. Want to Upgrade?


To: Vector1 who wrote (7243)12/1/1999 7:33:00 PM
From: tnsaf  Respond to of 9719
 
INIS is the provider of the isotope for NERX's multiple
myeloma therapy that was mentioned by RWR.


Friday October 22, 9:00 am Eastern Time

Company Press Release

SOURCE: International Isotopes Inc

International Isotopes Inc Announces
Agreement With NeoRx Corporation

- Manufacturing Process Line to be Designed for Production of Ho-166 -

DENTON, Texas, Oct. 22 /PRNewswire/ -- International Isotopes Inc (Nasdaq: INIS, BSE: ITL) (I3), a
commercialization partner for contract manufacturing of finished radiopharmaceuticals and a producer of
radioisotopes, pharmaceutical grade radiochemicals and medical devices, today announced that the
Company has entered into an agreement with NeoRx Corporation (Nasdaq: NERX - news). Under the
agreement, I(3) will design the commercial manufacturing process line for NeoRx's Skeletal Targeted
Radiotherapy (STR) product for the treatment of multiple myeloma.

STR combines the radionuclide Holmium 166 (Ho-166) with a small molecule that targets bone tissue,
resulting in the delivery of high radiation doses to the bone without exposing normal tissues to excessive
amounts of radiation. NeoRx is currently conducting clinical trials in patients with diagnosed multiple
myeloma to study the effects of combining escalating doses of STR with standard high dose myeloma
therapies. NeoRx believes that STR may also be applicable to the treatment of other diseases that arise in,
or spread to, the bone marrow such as other blood cancers, prostate and breast cancer.

[snip]
Full release at biz.yahoo.com

NERX will be reporting more interim results of SRT at ASH.
According to recap.com this is a P I/II that started this
year.


Tuesday November 30, 9:00 am Eastern Time

Company Press Release

SOURCE: NeoRx Corp.

NeoRx's Multiple Myeloma Study With Targeted Radiotherapy to be Updated at ASH

Recent Thalidomide Results Heighten Interest in New Multiple Myeloma Therapies

SEATTLE, Nov. 30 /PRNewswire/ -- NeoRx Corporation (Nasdaq: NERX - news) said further interim
data of its Skeletal Targeted Radiotherapy (STR) product in patients with multiple myeloma will be
presented by Dr. Richard Champlin, Chairman of the Department of Blood and Bone Marrow
Transplantation (MD Anderson Cancer Center, Houston, TX) and one of the principal investigators of the
study, at the American Society for Hematology (ASH) meeting in New Orleans on December 7, 1999.

Clinical interest in this fatal bone disease and in promising new therapies has been heightened by a recent
New England Journal of Medicine article (November 18, 1999, pps. 1565-1571) describing the use of
thalidomide for patients who had relapsed after high dose therapy.

The ASH presentation on NeoRx's experimental radiation product will report safety data on more than 45
patients and tumor response information on at least 27 of those patients for whom efficacy evaluation is
completed.

At the International Society of Experimental Hematology meeting (Monaco, July 1999) and the
International Multiple Myeloma Workshop (Stockholm, September 1999), the principal investigators
reported that 9 of 17 patients had achieved complete response.

[snip]
Full release at biz.yahoo.com

Jason