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Biotech / Medical : Keravision(kera) -- Ignore unavailable to you. Want to Upgrade?


To: wily who wrote (311)1/10/2000 9:19:00 AM
From: gao seng  Read Replies (1) | Respond to of 338
 
Corneal Rings:

Does this article relate to KERA? A quick search at 10kwizard.ragingbull.com on "corneal rings" returns mostly KERA links.

10kwizard.ragingbull.com

Corneal Rings An Alternative To Laser Surgery

For more than three years, 20 million mildly nearsighted Americans have been caught in a dilemma: Stick with glasses and contacts, or pay for popular new laser surgery to fix their vision.
Nearly a million a year opt for surgery. But, many others still feel skittish about the risks and permanence of laser procedures. Now, they have a third choice, say doctors at the University of Michigan Health System.

The new procedure, available at the U-M's Kellogg Eye Center and other select locations since early 1999, fixes eyesight by implanting a tiny plastic ring into each eye. After several months of seeing the results for themselves, U-M eye surgeons say the quick, effective and reversible operation could provide a needed alternative for about half of all nearsighted people.

The implants are called corneal rings. They correct the shape of the cornea, the clear "window" that covers the front of the eye, altering the path that light takes as it passes through the eye and focusing it correctly on the retina at the back of the eye.

Nearsightedness is caused by corneal steepness, or increased length of the eye. As a result, the eye bends, or refracts, light incorrectly and focuses it before it reaches the retina. Corrective procedures for the problem - whether with lasers or implants - are called refractive surgery.

"The advantages of the corneal ring procedure are that the rings are potentially removable, so the procedure can be reversed, and also that the center part of the cornea is not directly affected by the surgery," says Alan Sugar, M.D., a corneal surgeon and associate chair of ophthalmology at the U-M, and one of the first surgeons trained to implant the rings.

Another advantage, he adds, is that the rings seem to correct sight better than laser procedures do, giving three out of four patients 20/20 vision and allowing half to see better than 20/20.

Still, he cautions, "There's no single procedure that's best for every patient, so we at the U-M offer a range of procedures for a range of individual patient needs."

Both the corneal rings and laser procedures underwent extensive testing before gaining approval from the Food and Drug Administration and becoming widely available. The first corneal ring implant to be approved is Intacs, made by Keravision. "The first patients treated were operated on in 1991," says Sugar, "and the long-term follow-up seems to be very good."

Still, some don't want to submit to a laser procedure that can't be reversed if new technology becomes available in coming years or if something goes slightly wrong - such as the haze, glare or nighttime "halo effect" reported by a minority of laser-treated patients. Studies of corneal rings showed they can be adjusted or removed without adverse affects.

On the other hand, the rings can only help those patients whose nearsightedness falls within minus one to minus three diopters, or optical measurement units.

Laser procedures like photorefractive keratectomy (PRK) or laser assisted in-situ keratomileusis (LASIK) have been approved for a wider range of vision problems. Those who are more severely nearsighted, farsighted or have an astigmatism caused by irregularly curved corneas, may have to wait several years before corneal rings are available to them.

For those who can consider corneal implants now, Sugar says, the operation is a relatively simple one performed on an outpatient basis. "It does require some technical skill, and it requires anesthesia in the form of eye drops. It takes about 15 minutes for each eye," he explains. The cost is comparable to laser surgery, about $2,000 per eye, though most insurance plans do not cover the expense. Recovery is rapid -- patients are usually back to work the next day.

So, Sugar says, patients who might be interested in the implants should consult with their eye doctors before deciding which optical option to choose.

Facts about nearsightedness and refractive surgery:

· An estimated 68 million Americans are nearsighted, about 20 million with a mild form.

· No procedure is 100 percent predictable, so some patients may sometimes need glasses.

· Studies show that 97 percent of corneal ring patients achieved 20/40 vision or better, 74 percent achieved 20/20 vision or better, while about 53 percent had 20/16 vision or better.

· Corneal rings are made of the same material used for years in some intraocular lenses to treat cataracts. - By Kara Gavin

Related websites:

UMHS Health Topics A to Z: Eye Care

U-M Kellogg Eye Center

American Academy of Ophthalmology: Refractive Errors and Surgery

[Contact: Kara Gavin, Andi McDonnell]

10-Jan-2000

unisci.com



To: wily who wrote (311)1/11/2000 10:27:00 PM
From: Phil  Read Replies (1) | Respond to of 338
 
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>>a gradual withdrawal of the short interest would maintain the price at current or slightly higher levels.<<

My experience with heavily shorted stocks is that rallies retrace to a high degree -- some quicker than others -- probably as a result of shorts re-entering.

**Perhaps the difference in our opinion relates to the speed at which the short covering occurs. If we have a too rapid run-up, you are probably correct about retracing. If the short position is covered gradually, i believe we will see a relatively stable price rise with little sustained back-sliding. I'm ok with either scenario.**
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>>there are a lot of areas within the realm of KVI that have the potential to produce strong, surprising, positive news<<

Like what? The procedure numbers are bad and that's put a strain on proctoring (not enough procedures to get doctors proctored in one session) which in turn has put a strain on training (staff is focusing on proctoring).

**Your statement that procedure #s are "bad" is simply incorrect. The strain on proctoring is a result of training 600 idocs instead of the anticipated 200.
As for surprises...well, that is why they are called surprises. No one expects them.
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>>The upswing in institutional ownership also can be interpreted as positively supporting this proposition<<

Institutional ownership swung up to over 40% and then back down to 30% after the revenue warning.

The only way I could see this move sustaining is if there is an offer on the table -- something I am suspicious of, but I'm taking my chances.

**I don't think a buyout is an option at this point. JMHO.

Institutions now own about 35%, up from around 20% six weeks ago. **

Good luck,
Phil