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To: David M. Gloss who wrote (4724)1/12/2000 10:40:00 PM
From: David M. Gloss  Respond to of 4891
 
As filed with the Securities and Exchange Commission on January 12, 2000.
Registration No. 333-_____
================================================================================

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM S-1
REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933

ADVANCED VIRAL RESEARCH CORP.
-----------------------------
(Exact name of Registrant as specified in its charter)

Delaware
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(State or other jurisdiction of incorporation or organization)

5129
----
(Primary Standard Industrial Classification Code Number)

59-2646820
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(I.R.S. Employer Identification No.)

200 Corporate Boulevard South, Yonkers, New York 10701
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(914) 376-7383 (Address and telephone number of Registrant's
principal executive offices)

Shalom Z. Hirschman, M.D., President
200 Corporate Boulevard South, Yonkers, New York 10701 (914) 376-7383
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(Name, address and telephone number of agent for service)
---------------
COPIES TO:
CHARLES J. RENNERT
Berman Wolfe Rennert Vogel & Mandler, P.A.
NationsBank Tower, Suite 3500
100 Southeast Second Street
Miami, Florida 33131-2130
(305) 577-4177 Phone (305) 373-6036 Fax
---------------
Approximate date of commencement of proposed sale of the securities to the
public: As soon as practicable after the effectiveness of this registration
statement.

SELLING SHAREHOLDERS

The following table sets forth certain information regarding the
beneficial ownership of the common stock as of the date of this prospectus by
each of the selling shareholders assuming the full exercise of certain warrants
and stock options. Unless otherwise indicated below, to our knowledge all
persons listed below have sole voting and investment power with respect to the
shares of common stock, except to the extent authority is shared by spouses
under applicable law. The information included below is based upon information
provided by the selling shareholders. Because the selling shareholders may offer
all, some or none of their shares, no definitive estimate as to the number of
shares that will be held by the selling shareholders after such offering can be
provided and the following table has been prepared on the assumption that all
shares offered under this prospectus will be sold.

POSITION WITH OR SHARES OWNED SHARES BEING SHARES OWNED
RELATIONSHIP TO BEFORE OFFERING (1)(2) SOLD IN AFTER OFFERING (3)
SELLING SHAREHOLDER ADVANCED VIRAL NUMBER % OFFERING(2) NUMBER %
------------------- -------------- ------ --- ----------- ------ --
Endeavour Capital Fund S.A. (4) Investor 19,736,842 6.1% 19,736,842 0 0.00%
Samuel Krieger (5) Counsel to Investor 5,000 * 5,000 0 0.00%
Ronald Nussbaum (5) Counsel to Investor 5,000 * 5,000 0 0.00%

Selling Shareholders Total Shares 19,746,842 6.1% 19,746,842 0 0.00%
Total Shares Outstanding after Offering 332,038,877
===========

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* LESS THAN 1%