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To: Steve Antonelli who wrote (5)	2/16/2000 6:58:00 PM
From: Steve Antonelli	Read Replies (1) \| Respond to of 20

02/16/00 AFFX - Biotech AFFX in IBD by: LyntonXLee 2/13/00 3:51 am Msg: 3160 of 3177 AFFX is featured in the New America page of Monday's Investors Business Daily. -------------------------------------------------------------------------------- messages.yahoo.com Author: jaalkr Number: of 224 Subject: Competing technology? Date: 2/15/00 9:02 PM Email this to a Friend Format for Printing Post New ? Post Reply ? Reply Later Problem Post ? Recommend it! Story in the New York Times 2/15, page D3, discusses a new genetics library technique that uses tiny polystyrene beads instead of a chip. The original scientific paper is published in the Proceedings of the National Academy of Sciences this week. IMHO, seems that this might become a cheaper and more efficient screening method than chip technology. Any thoughts? boards.fool.com Author: frflyer Number: of 224 Subject: Re: Is AFFX the next Snapple? Date: 2/16/00 3:35 AM Email this to a Friend Format for Printing Post New ? Post Reply ? Reply Later Problem Post ? Recommend it! Yowman; The PE Corp you are talking about, is not Perkin Elmer. PE Corp, comprised of PE Biosystems(PEB) and PE Celera(CRA), sold off the Perkin Elmer analytical instruments business and the name Perkin Elmer. PE Biosystems has a market cap of about $15B-$17B And I believe it is they who have the PCR patents. There is no stock for PE Corp, just the two tracking stocks. frflyer boards.fool.com Author: frflyer Number: of 224 Subject: Re: Competing technology? Date: 2/16/00 3:48 AM Email this to a Friend Format for Printing Post New ? Post Reply ? Reply Later Problem Post ? Recommend it! jaalkr; There are several companies using bead technology. (microspheres) Ilumina a private company uses beads with fiber optics Luminex similar to Ilumina, uses diode lasers; is going public soon (LMNX) Lynx (LYNX) uses beads in a different way. Symx ( ? )also uses bead technology I mix microspheres with epoxy to fair the hull of a boat, but that's a another story. boards.fool.com By: RedDot Reply To: None Monday, 24 Jan 2000 at 9:27 AM EST Post # of 106 Look at NGEN.....piece of article below....Like Affymetrix, Nanogen applies semiconductor manufacturing advances to DNA diagnostics; however, its technologies are very different. Whereas Affymetrix uses a nonelectronic photolithographic process to hybridize genes, Nanogen electronically addresses DNA to force hybridization. The size of an Intel 286 chip, Nanogen's Apex draws DNA strand-mates together with a positive electronic charge. Then it switches to a negative charge, and only the hybridized strands remain in an embrace. Hybridization with Nanogen's Apex is faster than with Affymetrix's GeneChip. Another significant difference is that Apex is essentially an ASIC, or reconfigurable electronic device, the likes of which are manufactured by the millions at Texas Instruments and elsewhere. Apex's DNA probes can thus be rearranged on the fly by software to test for new diseases. ragingbull.com By: proteomics Reply To: 99 by stardance Thursday, 3 Feb 2000 at 7:24 PM EST Post # of 106 Important info? Not! Affymetrix has NOTHING to do with gene therapy! They make chips that can be used, potentially, to diagnose a host of illnesses. The chips allow doctors to tailor a patients treatment to their genetic makeup, reducing the side effects and increasing the effitiveness. Gene therapy is a whole other ball game, and not one that affymetrix is even looking towards. For affymetrix, think perfect diagnostics. Not therapy. ragingbull.com