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Biotech / Medical : Gliatech (GLIA) -- Ignore unavailable to you. Want to Upgrade?


To: jeffbas who wrote (1428)3/2/2000 7:20:00 AM
From: biowa  Respond to of 2001
 
Jeff,

but have an exceptionally critical eye before buying, which is what I have been contemplating - without much conviction so far ??

On Janssen from the GLIA website:

In collaboration with Janssen Pharmaceutica, N.V., a wholly owned subsidiary of Johnson and Johnson, Gliatech is identifying and characterizing compounds that will minimize the glial cell inflammatory response in Alzheimer's disease. The Company believes that these compounds may slow down or inhibit disease progression.

Gliatech is pursuing a two-pronged approach to developing glial-related treatments for Alzheimer's disease. The first approach focuses on developing compounds that block the glial cell activation caused by beta amyloid, thus inhibiting cytokine release and the resulting inflammation. The second approach seeks to identify compounds that block the damaging complement proteins that are activated by the beta amyloid peptide.

Gliatech has screened Janssen's library of compounds and has identified several compounds that offer therapeutic potential. These compounds are being used to develop more potent and selective compounds, which will be examined in animal models and additional preclinical tests.


AND

Finally, in October 1997, Janssen Pharmaceutica, a wholly owned subsidiary of Johnson & Johnson, extended its collaboration agreement with Gliatech for the Alzheimer's disease research program.

biowa