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Biotech / Medical : Biotechnology Value Fund, L.P. -- Ignore unavailable to you. Want to Upgrade?


To: tommysdad who wrote (1545)3/15/2000 1:31:00 AM
From: scaram(o)ucheRead Replies (2) | Respond to of 4974
 
Heh, heh. You're right up there with me when it comes to picking the correct day for this sort of stuff.

Good news, I agree. I don't know enough about the target other than to say that the PR reads quite nicely. Will wait for Biotech Jim or Neuroinvest or ??? to bring us up to speed on GnRH antagonists.

You know this molecule?



To: tommysdad who wrote (1545)3/15/2000 8:01:00 AM
From: scott_jiminezRespond to of 4974
 
A postdoc in the lab where I did my graduate work studied GnRH. His research-in-progress presentations were always 'interesting' since the graphic discussion of manipulating XX physiology was either extremely amusing or extremely disgusting. No middle ground.

In any event, he is a co-author on this abstract ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7852501&dopt=Abstract which indicates that Dr. Vale and friends must keep in mind the direct effects of GnRH at sites outside the hypothalamic/pituitary/gonad axis.

I'm unfamiliar with much of the work in this field so I don't know if 'non-axis' effects are significant or, more importantly, well understood.