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Biotech / Medical : STEM -- StemCells, Inc. -- Ignore unavailable to you. Want to Upgrade?


To: scaram(o)uche who wrote (454)4/17/2000 5:00:00 PM
From: scaram(o)uche  Read Replies (1) | Respond to of 805
 
10-K out......

The following table lists the potential therapeutic indications for and
current status of CytoTherapeutics' primary research and product development
programs and projects and is qualified in its entirety by reference to the more
detailed descriptions of such programs and projects appearing elsewhere in this
Report. The Company continually evaluates its research and product development
efforts and reallocates resources among existing programs or to new programs in
light of experimental results, commercial potential, availability of third party
funding, likelihood of near-term efficacy, collaboration success or significant
technology enhancement, as well as other factors. The Company's research and
product development programs are at relatively early stages of development and
will require substantial resources to commercialize. There can be no assurance
that the Company will successfully develop any product or obtain regulatory
approvals, enter clinical trials, achieve other milestones or commercialize any
products in accordance with currently anticipated timetables, or at all.

<TABLE>
RESEARCH AND PRODUCT DEVELOPMENT PROGRAMS
PROGRAM DESCRIPTION STAGE/STATUS(1)
<S> <C>
HUMAN NEURAL STEM CELL PRECLINICAL
Repair or replace damaged CNS - IN VITRO ability to initiate and expand stem
tissue (including retinal cell-containing human neural cultures and differentiation
degeneration and the results into three types of CNS cells
of certain genetic disorders) - Direct isolation of neurosphere-initiating stem cells from
brain
- IN VIVO demonstration of proper differentiation and
engraftment of human neural cell cultures containing CNS
stem cells in rodent CNS
PANCREATIC ISLET STEM CELL RESEARCH
Repair or replace damaged - Identified cell surface marker used to identify, isolate
pancreatic islet tissue and culture pancreatic islet stem cells
- Commencing small animal testing
LIVER STEM CELL RESEARCH
Repair or replace damaged Discovery program to identify, isolate and patent human stem
liver tissue (including the cells for the liver
results of certain metabolic
genetic diseases)
</TABLE>

(1) "Research" refers to early stage research and product development activities
IN VITRO, including the selection and characterization of product candidates
for preclinical testing. "Preclinical" refers to further testing of a
defined product candidate IN VITRO and in animals prior to clinical studies.