Silicon Investor (SI) -- The First Internet Community

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Biotech / Medical : Regeneron Pharmaceuticals -- Ignore unavailable to you. Want to Upgrade?

To: Miljenko Zuanic who wrote (430)	4/24/2000 11:40:00 PM
From: Miljenko Zuanic	Read Replies (1) \| Respond to of 3559

Grain by grain,...but what is holding that partnering plan???? IL-4 Level Linked to Dust Mite Sensitivity in Asthmatic Children -------------------------------------------------------------------------------- WESTPORT, Apr 24 (Reuters Health) - Interleukin 4 (IL-4) production by peripheral blood cells correlates with serum IgE antibody against house dust mites in asthmatic children, Japanese researchers report in the February issue of the Journal of Allergy and Clinical Immunology. Dr. Mitsuaki Kimura and colleagues from Shizuoka Children's Hospital, who note that IgE antibody may play an important in bronchial asthma, sought to determine what cytokines might be associated with upregulation of IgE synthesis against house dust mite in sensitized children. The researchers collected peripheral blood samples from 23 such asthmatic children and from 15 nonatopic controls. Stimulation with house dust mite allergen caused significantly higher production of IL-4 and IL-13 in the samples from the asthmatics than in those from controls. In addition, IL-4 production showed a "distinctly stronger" positive correlation with house dust mite-specific IgE antibody than did production of IL-13. The findings suggest, the researchers conclude, that in children with bronchial asthma "the action of IL-4 is more potent than IL-13 on in vivo IgE antibody production" against house dust mites. J Allergy Clin Immunol 2000;105:327-332