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Biotech / Medical : Repligen Corp (RGEN) -- Ignore unavailable to you. Want to Upgrade?

To: Curtis E. Bemis who wrote (224)	5/22/2000 10:46:00 PM
From: Scott H. Davis	Respond to of 395

Another "marker" for a pre-disposition to Autism is a very flawed and unbalanced immune system (research by Reed Warren and S. Gupta) The predisposition comes into play when baby/toddler/young child either contracts an infection such as measels, or is given an innoculation, frequently MMR with "live" virus. Trashes the GI tract (See Lancet, Feb 98) Leads to intestinal permiability & the release of Gluten and/or casein peptides, which contain opioid sequences, which if the escape the GI tract, cross the blood brain barrier, effecting brain development & chemestry. One of the reason autistic children have such frequent self-stimming and self injurious behavior is that they're "doped up" So testing the immune system 1st before vaccinating could avert a multitude of cases, but that's pretty inexpediant for policy based medicine. So the huge increase in autism associated with an increasing # of vaccinacions and a progressively early age results in an unfortunate increasing market for Secretin. FYI Scott In autistic children we have very good results as documented with STRICT diet (Knivsberg SA-M et al (1990) Brain Dysfunct 3:315-327 and also Reichelt Klet al (1991) Brain Dysfunct 4:308-319). In the last publication evidence for the identification of bovine casomorphin 1-8 immunoreactive peptides was reported, and opioids are formed from food proteins in the gut. Also extremely important is the fact that everybody takes up bioactive peptides and also trace amounts of protein from the gut (Gardner MLG (1994) in Physiology of the gastrointestinal tract (Johnson LR : edit) Rave Press, NY pp 1795-1820), That this is so can be seen from the fact that we all have IgG antgibodies to food proteins. Because there are 15 opioid sequences in one molecule of gluten (Fukudome and Yoshokawa (1991) Febs lett 296:107-111) even trace amount so protein uptake can be catastsrophic if not properly broken down.