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To: marc ultra who wrote (13719)5/12/2000 8:33:00 AM
From: J. M. Blackburn  Respond to of 15132
 
Marc OT
Thanks for info on Phase 1 tests. Do you have a feel for the financial end?

Will ENMD have the cash to go forward with these tests? To get the cash will share holder's equity be substantially diluted?

Thanks, Jim



To: marc ultra who wrote (13719)5/12/2000 2:07:00 PM
From: Beobe  Read Replies (1) | Respond to of 15132
 
marc,

Your long and informative message could be a
lot easier to read if you popped in a
paragraph now and then.

Regards.

Robert



To: marc ultra who wrote (13719)5/14/2000 9:43:00 PM
From: marc ultra  Respond to of 15132
 
OT:ENMD. Could drop sharply again tomorrow. Chicago Tribune now out with negative article

chicagotribune.com

While not good news far too early to assess drug.

The dose and method of administration were both suboptimal but somewhat dictated by FDA as primarily a safety trial. Suboptimal dosing against large bulky tumors that have failed all conventional chemo likely too much of a challenge

Main issue may be to assess if an anti-angiogenic effect did in fact occur as intended. If yes as has been suggested, more appropriate dosing by continuous infusion may be the answer. This has just gotten underway in Amsterdam I believe.

Will know better late in the year . The WSJ reporter who has been writing negative stories on this that proved incorrect before it was given to humans, is snooping around Raging Bull message board and might also pile on with a negative article. The company may be pushed to give a conference call if stock falls again.

Marc