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To: Ron McKinnon who wrote (23340)	5/17/2000 1:32:00 PM
From: John Solder	Read Replies (1) \| Respond to of 53068

Can someone clue me in as to what this means ? I just got this from DLJ: We are writing to advise you that NOTICE HAS BEEN RECEIVED THAT VERTEX PHARMACEU TICALS INC., INTENDS TO FILE A SHELF REGISTRATION STATEMENT WITH THE SECURITIES AND EXCHANGE COMMISSION FOR THE ABOVE MENTIONED ISSUE. HOLDERS WHO WISH TO INCLUDE THEIR SECURITIES IN THE SHELF REGISTRATION STATEMENT MUST COMPLETE AND RETURN THE RELATED QUESTIONAIRE TO THE COMPANY ON OR BEFORE 5 /30/00. NOTE: HOLDERS WILL BE RESPONSIBLE FOR COMPLETING AND SENDING THE DOCUMENTS TO TH E COMPANY'S LEGAL COUNSEL BY 5/30/00.