To: Graham Marshman  who wrote (4021 ) 6/8/2000 10:00:00 PM From: JMarcus     Read Replies (1)  | Respond to    of 4028  
The following shareholder update (dated May 24, 2000) appears on the company's website: cytogenix.com                                  The SEC Saga Continues?                                  We have so far filed five amendments to our original 10SB, but have yet to                                 completely satisfy the SEC examiners. It begins to seem that each answer                                 we provide provokes two new questions.                                  We take only a little comfort in the fact that we are not alone? the SEC is                                 badly backed up trying to respond to thousands of filings and amendments                                 from companies of all types, most of which are dealing with technologies and                                 structures that everyone understands. As a leading edge biotech, we have a                                 particular challenge in presenting the specialized nature of genetics and                                 molecular biology in language that is familiar and understandable to people                                 whose daily focus is financial data.                                  Knowledge of other companies? experience and our own persuades us that it                                 is futile to try to predict how long the process will take, but the fundamentals                                 of CytoGenix are unchanged. We continue to plow new ground, plant the                                 seeds, and cultivate the newest technologies, confident of the long-term                                 rewards for those who persevere. We are conducting experiments in our own                                 laboratories and have initiated two new sponsored research programs at a                                 local research institution. The ultimate value of the TroVec technology is in no                                 way diminished by the current compliance challenge. It is time consuming,                                 frustrating, aggravating, and expensive. It is also unavoidable in today?s                                 complex regulatory environment.                                  We appreciate the assurances, comments, and concerns of our shareholders                                 as expressed in your calls and emails. Feel free to contact us at any time,                                 but be assured that any updates and news of progress will be promptly                                 posted on the website then be the subject of an appropriate press release.                                  In the interim, we suggest that anyone wishing to trade our stock consider                                 E-trade. E-trade will execute limit orders (most online brokers won?t) and they                                 promptly quote the most recent transaction along with high, low and volumes.