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Biotech / Medical : STEM -- StemCells, Inc. -- Ignore unavailable to you. Want to Upgrade?

To: Jon Koplik who wrote (472)	5/31/2000 6:50:00 AM
From: scaram(o)uche	Read Replies (1) \| Respond to of 805

Nice to see Harry cited at the end..... always one to make gutsy calls, even if they tick some off. Great article, lousy representation of STEM and how the business plan falls into the "expansion of autologous cells" camp. Was wondering why the stock was relatively weak yesterday. Thanks!

To: Jon Koplik who wrote (472)	6/4/2000 9:35:00 PM
From: Jon Koplik	Read Replies (1) \| Respond to of 805

Another NYT article about stem cells. June 2, 2000 Study Suggests Brain Stem Cells Can Convert Into Other Tissues By THE ASSOCIATED PRESS WASHINGTON, June 1 -- Research in mice suggests that stem cells from the adult brain can be nurtured into heart, liver, muscle and other tissues. The finding may eliminate the ethical dilemma now blocking stem cell studies that use human fetal tissues, experts say. The mouse study, by researchers in Sweden, found that neural stem cells taken from the central nervous system of adult mice and transferred to mouse and chicken embryos were converted into the cell types that are found in a variety of body tissues and organs. One part of the study, which is being published on Friday in the journal Science, showed that some neural stem cells converted to become part of a beating heart in a mouse embryo. Ihor R. Lemischka, a professor of developmental biology at Princeton University, said that if the research could be confirmed in human cells, it would "nip in the bud" the moral and ethical concerns that now block federal money for human embryonic stem cell research. Under federal law, the National Institutes of Health is forbidden to finance human embryo research. The objection to such research is that such cells must be taken from an embryo or a fetus, usually after an abortion. Experts believe that stem cells may eventually be used to grow new body parts to replace failing organs, or to treat brain, bone or blood disorders by replacing diseased cells with healthy ones grown from stem cell precursors. In the study, scientists at the Karolinska Institute in Stockholm separated neural stem cells from adult mouse brains and grew them in large numbers in the laboratory. Stem cells in the culture carried a genetic tag so they and their descendants could be identified. The cells were then inserted into fertilized chicken eggs or into mouse embryos. A later analysis showed that some of the transplanted stem cells converted into different organ tissues in the developing embryo. Copyright 2000 The New York Times Company