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To: wlheatmoon who wrote (1178)6/1/2000 6:42:00 PM
From: John Pitera  Read Replies (2) | Respond to of 2850
 
the ideal thing would be to be able to detect early cancer and metastatic recurrence before clinical evidence

does it appear they can do that? what would they have
to do.

wow they were up 70% today. I never got out of the
last thousand, and I've still got some of this in my
PA..... it's a real black hole things get in there and
never get out..... -g-

------------


I just see the 8 million women taking progestin and
estrogen have a much greater chance of getting breast
cancer

Hormone therapy found to boost risk of breast cancer

June 1, 2000
Web posted at: 11:26 AM EDT (1526 GMT)

SEATTLE (AP) -- Use of a hormone-replacement therapy with estrogen and progestin can more than double the risk of a form of breast cancer, researchers reported today in the journal Cancer.

Scientists at the Fred Hutchinson Cancer Research Center studied 537 King County women at least 50 years old who had breast cancer from 1988 to 1990. They were compared with 492 women who had not had the disease.





Scientists found a 2.6-fold higher incidence of lobular breast cancer in women who took the combination therapy for at least six months and an average of four years.

The reason only one form of cancer increased is "a question for the future: Do some women have certain characteristics that make them more susceptible to lobular cancer when using replacement therapy?" said Dr. Christopher Li, the study's lead author.

About 85 percent of invasive breast cancer cases are in the ducts that carry milk to the nipple. Lobular cancer occurs in the milk-producing lobules and affects about 10 percent of breast-cancer cases.

About 8.6 million women in the United States take the combination therapy treatment and 12 million take estrogen alone.

The hormones reduce the risk of broken bones from osteoporosis and ease menopausal symptoms. In women who have not had a hysterectomy, progestin is used to lower the risk of endometrial cancer.

Earlier studies, including two this year, indicated a heightened risk of breast cancer among women using combination hormone therapy for at least five years but not among those using estrogen alone.

In a related study, Li found a 35 percent increase in lobular cancer between 1988 and 1995.

"Although preliminary, our studies suggest that the incidence of lobular breast cancer is increasing nationwide and that the use of postmenopausal hormone replacement therapy, specifically the use of combined estrogen plus progestin preparations, may be contributing to this increase," Li said.

He said more studies were required to confirm the findings.



To: wlheatmoon who wrote (1178)6/1/2000 7:53:00 PM
From: John Pitera  Read Replies (1) | Respond to of 2850
 
How big is this???--Intel, RealNetworks in Web video pact

By Michael Tarsala, CBS MarketWatch
Last Update: 5:51 PM ET May 24, 2000 NewsWatch

SAN JOSE, Calif. (CBS.MW) -- RealNetworks, one of Microsoft?s key competitors in Internet audio and video software, announced a new multimedia software product Wednesday developed in collaboration with Intel.

Intel and RealNetworks (RNWK: news, msgs) made available a test version of new software that the companies say enhances the herky-jerky pictures associated with most Internet video. The software will become part of a package called RealSystem 8 software.

The software was debuted at a company event in San Jose, Calif., with director Francis Ford Coppola on-hand for a demonstration.

"We've been co-developing this with Intel for more than a year," said Ben Rotholtz, RealNetworks' media systems general manager. "This is our third-generation video with Intel (INTC: news, msgs). What we introduced today is radically different."







The software promises near-DVD quality video on the Internet when viewed at high speeds, according to RealNetworks executives. Cable modem and DSL subscribers should expect VHS-quality video when viewing pictures on the software using half the screen. Consumers whoDial-up Internet subscribers also should expect vast improvements over past technology, including past RealNetworks software versions, company executives said.

"You're getting video that's worth paying for," Rotholtz said. " It initiates a whole new wave of business models that will accelerate the mass market. There's the opportunity for pay-per-view and subscription Internet video."

The new software relates to an announcement made Monday of a new version of RealNetworks' free audio and video player dubbed Real Entertainment Center that is slated to compete with Microsoft's Windows Media Player and Apple's QuickTime.

The software combination promises to heat up the ongoing battle between Real, Microsoft (MSFT: news, msgs) and Apple in Internet audio and video software. Both Microsoft and Apple also have had recent product announcements.

"We?re all doing our best to drive innovation ... we continue to drive hard-and-fast to deliver the best-looking video," said Frank Casanova, an Apple marketing executive. Apple announced Tuesday that Kodak is putting the Apple QuickTime video file format inside of digital cameras.

As part the new RealSystems 8 software, announced new technology that aims to improve the streaming process of Internet games. The company also said it's integrating nCUBE's video-on-demand software into the software that's aimed at broadcasters. The new server-based software will be offered by the two companies, and will deliver video at speeds of at least 200 kilobits per second

In still another announcement, RealNetworks announced S3 Inc.'s (SIII: news, msgs) music download hardware called the Rio Receiver will work with RealNetworks' audio software.

It was a busy news day for Intel. The company also announced plans to invest $2 billion to expand a wafer fabrication facility, unveiled the Pentium III processor and agreed to team with Cable & Wireless HKT to provide to joint e-business offerings in Asia.

RealNetworks? shares rose 2 3/4 to 34 15/16 Wednesday.





To: wlheatmoon who wrote (1178)6/2/2000 12:20:00 AM
From: John Pitera  Read Replies (2) | Respond to of 2850
 
Broadband May 23 2000 2:59PM CST

The Need for Speed
by Chris Connor

With the explosion of on-line multimedia offerings such as movies, multiplayer computer games, and business applications, consumers have demanded faster access to these multimedia offerings than they have traditionally received via standard 56k modems - much faster in fact. Companies crave higher access speeds as well, because faster access will cut down on the cost of materials like CDs, paper, and video tapes. For example, the porn industry wants faster Internet connections so its customers can just download movies straight from a site, which eliminates the need for buying video tapes for each potential customer. The music industry also desires faster connection speeds, since most songs are a few megabytes in size and most modems today run at 56 kilobits per second. The answer to this need for speed is broadband A.K.A. "fat pipes".

Broadband comes in several different forms, but the two big ones right now are cable modems and Digital Subscriber Lines (DSL), with fiber optics looming in the background as the biggest source of broadband for the future. Cable and DSL offer users connection speeds that are exponentially higher than 56k modems at around 1.5 megabits per second. In addition, both technologies stay connected to the Internet while a regular phone number must connect to the Internet each time a user wants to get on line and can be automatically disconnected during the worst possible times - like while chatting, playing games on-line, or downloading big files.

However, speed and the always-on feature are where the similarities between cable and DSL end. Cable access does not require a phone line, offers the Internet Service Provider (ISP) and high-speed connection from the same company, does not require long contracts, and it distributes bandwidth (the amount of data that can be transmitted in a fixed amount of time) that is shared by the cable users on a particular network. On the other hand, DSL offers a one-to-one connection between the customer and the ISP, and allows the customer to choose from several ISPs. With DSL, the data is transmitted over regular phone lines so DSL is better suited to handling two-way communications than cable - which was originally used for just receiving information.

What is the best way for investors to profit from the booming broadband industry? In light of the already intense competition among companies offering broadband access, investors would be wise to avoid that area and concentrate mostly on the equipment suppliers for DSL and cable access. Broadband equipment suppliers should continue to benefit from the immense growth in the industry, even as a plethora of broadband access providers emerges, because technology is much harder to duplicate than services.

The dominant cable ISP is At Home {ATHM}, but Terayon {TERN}, Broadcom {BRCM}, and Conexant {CNXT} offer better ways to invest in broadband over cable. Broadcom and Conexant make the chipsets for cable modems while Terayon makes the actual cable modem using its own proprietary technology called S-CDMA. Although Conexant is one of the biggest communications chip makers and is rapidly growing its revenues, <b<Broadcom and Terayon appear to have greater futures in broadband access over cable due to tighter degrees of focus and superior cable technologies. Terayon uses its version of CDMA (primarily a wireless technology), S-CDMA (Synchronous-Code Division Multiple Access), to eliminate noise on even the oldest cable systems and to efficiently use bandwidth by differentiating the data using codes. Broadcom dominates the cable modem chip market because its chips have become the industry standard in a way similar to the way Intel's chips have become the standard in the realm of PCs. In fact, Broadcom looks to be one of the broadband elite with its cable modem chip leadership and a growing presence in DSL, broadband wireless, and gigabit Ethernet (a local area networking (LAN) technology). Broadcom also recently started an optical networking division.

Although there are roughly three times more cable modem subscribers than DSL subscribers in North America, DSL does have a pronounced advantage over cable because of its one-to-one connection between the customer and the ISP. In other words, DSL customers do not have to share bandwidth with their neighbors. Leading the pure-play DSL pack are two companies that have been public less than one year: GlobeSpan {GSPN} and Copper Mountain Networks {CMNT}. Both Broadcom and Texas Instruments {TXN} are significantly larger companies that make DSL chipsets, but they are not pure DSL plays. GlobeSpan is also a leading developer of DSL chip sets and Copper Mountain Networks is a leading comprehensive provider of DSL solutions. Other major players include Adtran {ADTN}, Paradyne {PDYN}, Efficient Networks {EFNT}, Aware {AWRE} and Pairgain Technologies {PAIR}. (Pairgain is scheduled to merge with ADC Telecommunications {ADCT}). Bringing up the rear are DSL companies like Interspeed {ISPD}, Metalink {MTLK}, Tut Systems {TUTS}, and Orckit {ORCT}.

Investors interested in companies that are building infrastructure for broadband access might want to check out broadband network companies such as Global Crossing {GBLX}, 360 Networks {TSIX}, Metromedia Fiber {MFNX}, and Level 3 Communications {LVLT}. These companies sell their bandwidth primarily to ISPs and telecommunication carriers, so the broadband networks also benefit from the insatiable need for broadband without being saturated by competition. The leading barrier to entry for the broadband network market is considerable start-up costs, which is why none of these companies have generated any real earnings yet. However, some companies are leasing capacity before their networks are completed. Basically, the broadband network companies are willing to build their networks now at huge losses so they can reap immense profits in the future when these networks are completed. The biggest of these companies, Global Crossing, has a fiber-optic network that almost spans the entire globe - serving 24 countries and over 200 major cites. Global Crossing has essentially built an international fiber optic network that competitors will have a hard, if not impossible, time duplicating because of the time and cost required to deploy fiber under the oceans. Broadband networks must also be wary of building networks with old legacy equipment, because the network must be upgradeable for the future. Many companies will try to equal what Global Crossing has done, but very few will succeed any time soon.

Investors also may want to take a long look at a few of the major fiber optic makers. Fiber optics is a key enabler of broadband because regular phone lines simply can not compare to fiber optic lines when it comes to broadband levels of speed. With that being said, the fiber optic component industry is characterized by a mixture of large companies with sustainable competitive advantages like JDS Uniphase {JDSU} and Corning {GLW}, small companies with dynamic products that have just began to generate revenue like Avanex {AVNX} and Sycamore Networks {SCMR}, and one young private optic company that could not only revolutionize the broadband industry but the wireless industry as well. That company, Terabeam, looks to take the "fiber" out of fiber optics. Since building fiber optic networks all the way to a business or residence is prohibitively expensive, Terabeam looks to transmit high-bandwidth optical signals (starting at 1 gigabit per second) through the air. Not only does transmitting optical signals through the air bypass expensive infrastructure to each building, it does not require a spectrum license the way that microwaves do. Another key advantage that Terabeam's optical signals have over radio frequency (RF) signals is that Terabeam's technology is point-to-multipoint, while the overwhelming majority of RF technologies are point-to-point. With point-to-point technology, additional networks are required to tie all the points together as opposed to Terabeam's technology, which will offer service to multiple customers through one hub. The biggest downside to Terabeam's technology is that it can send an optical signal only 3 kilometers - so this limitation rules out using the technology in all rural and most residential areas. Nevertheless, Terabeam accelerates the practicality of an all-optical network because it offers a solution to the "last mile" (connection to the actual user) problem. All-optical networks benefit the whole fiber optic component industry because this industry supplies the building blocks for such networks.

A second key enabler of broadband that deserves attention from investors is digital signal processing (DSP). DSP is essentially enabling traditional copper phone lines to carry high-speed data because it compresses video, images, and voice into more transmittable sizes. DSP also boosts the capacity of Cable TV systems, which allows them to offer the hundreds of channels that have been derided as being excessive. According to Broadband Access Technologies by Albert Azzam and Niel Ransom, DSP "is even allowing power lines and home electrical wires in the wall to be used as high-speed data transmission lines". The big four companies involved with DSP are Texas Instruments, Lucent Technologies {LU}, Motorola {MOT}, and Analog Devices {ADI}. However, Texas Instruments dominates the DSP market with close to a 50 percent market share.

Stay tuned as Wall Street City will analyze several key companies in the broadband industry over the next few months. Additionally, the major areas of the broadband industry will be explained in greater depth. Here are the stories that have followed this initial story thus far.

DSL: The Baskin Robbins of Broadband