Silicon Investor (SI) -- The First Internet Community

STOCKTALK

We've detected that you're using an ad content blocking browser plug-in or feature. Ads provide a critical source of revenue to the continued operation of Silicon Investor. We ask that you disable ad blocking while on Silicon Investor in the best interests of our community. If you are not using an ad blocker but are still receiving this message, make sure your browser's tracking protection is set to the 'standard' level.

Biotech / Medical : Elan Corporation, plc (ELN) -- Ignore unavailable to you. Want to Upgrade?

To: Ilaine who wrote (990)	6/6/2000 1:58:00 PM
From: Pseudo Biologist	Read Replies (1) \| Respond to of 10345

This report is a little weird, because TNF-alpha is a cytokine, not a gene. Not really that weird, a cytokine is, of course, a protein and proteins are coded by genes. So we have gene (DNA) => mRNA => protein. If you block the gene or the mRNA, say with antisense, then you prevent the protein from ever being produced. Remicade and Enbrel work at the protein level interacting with, and neutralizing, the TNF-alpha cytokine. Blocking the specific gene itself should, in theory, achieve the same purpose. PB