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Biotech / Medical : Regeneron Pharmaceuticals -- Ignore unavailable to you. Want to Upgrade?

To: Miljenko Zuanic who wrote (449)	6/20/2000 12:14:00 PM
From: juneau_boy	Read Replies (1) \| Respond to of 3559

If these devices were ever considered competition, they are running into heavy weather now... cnnfn.com

To: Miljenko Zuanic who wrote (449)	6/21/2000 8:27:00 PM
From: Miljenko Zuanic	Read Replies (1) \| Respond to of 3559

Sumitomo interest? United States Patent 6,077,829 Tanaka , et al. June 20, 2000 -------------------------------------------------------------------------------- Stable pharmaceutical composition of BDNF Abstract A stable pharmaceutical composition of brain derived neurotrophic factor (BDNF) in the form of an aqueous solution or lyophilized one being suitable for a long-term storage, which contains a surfactant, especially nonionic surfactant (e.g., Tween 80) of 0.001 to 10%, whereby the polymerization and the denaturation of BDNF are inhibited, and the biological activities of BDNF are maintained for a long time. The lyophilized composition can be made more stable by addition of a sugar alcohol (e.g., mannitol) and/or an amino acid (e.g., glycine). -------------------------------------------------------------------------------- Inventors: Tanaka; Katsumi (Takatsuki, JP); Kumano; Masashi (Mino, JP) Assignee: Regeneron Pharmaceuticals, Inc. (Tarrytown, NY); Sumitomo Pharmaceuticals Company, Limited (Osaka-fu, JP) Appl. No.: 180884 Filed: November 16, 1998 U.S. Class: 514/21; 514/12 Intern'l Class: A61K 038/22 Field of Search: