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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: aknahow who wrote (13987)7/5/2000 11:37:46 AM
From: Bluegreen  Respond to of 17367
 
George, where was the imaginary peptide blocker in Phase II Meningo. and Phase II Hemo Trauma???? Maybe it was in hiding and only decided to come out when N got larger???



To: aknahow who wrote (13987)7/5/2000 12:10:49 PM
From: Cacaito  Read Replies (3) | Respond to of 17367
 
Rk new the blood bpi (up to 15x), and xoma did not? WORST!

xoma designed a pII and PIII, wasted many million$ just to find out now from RK that the blood transfusion mess up the study!

Irresponsible at best, Stupid at worst from xoma not to realize that.

Blue, yes reserve all your recommendations on xoma until the data is out!

Gw, Do you still buy that bridge? that control group did "inexplicablly" 50% better! Were not you that post about "bias" in research publication in the yahoo xoma club right after the Lilly zovant press release? Does it apply to P. Scanon Viena pIII trauma presentation? NO, cause it does not fit in your belief in bpi!



To: aknahow who wrote (13987)7/5/2000 4:33:07 PM
From: Oak Tree  Read Replies (1) | Respond to of 17367
 
At the risk of being further blasted,
(1) I understand that everyone got two units
(2) I understand that therefore everyone got natural BPI and there was not control arm
(3) I didn't understand that Robert was a BPI believer and thought that the trial failed because there was no true untreated arm. That issue is relevant also.

I guess what some of you might not have understood (and perhaps I didn't make it clear) was that the inhibitor would support the utility of BPI in high dose.

I think it is also relevant to note that the paper suggested that not only was there BPI in blood, patients who got blood did poorly. While this is almost certainly related to the degree of trauma, it does not support an advantage of BPI.