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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: aknahow who wrote (14002)7/6/2000 7:44:07 AM
From: Oak Tree  Respond to of 17367
 
I like this discussion group. You are a lot of fun. Anyway, here is the quote that is so controversial.

BPI was found in all units of packed red cells tested at concentrations up to 15
times preoperative plasma levels in patients. …. Intraoperative PC
transfusions do contribute to the inflammatory response after cardiac surgery both by
enhancing part of the response and by directly changing plasma concentrations of
inflammatory mediators. Furthermore, these data show that intraoperative PC transfusion
is associated with a worse postoperative performance.

Chest 1999 Nov;116(5):1233-9
Impact of blood transfusions on inflammatory mediator release in patients undergoing cardiac surgery.
Fransen E, Maessen J, Dentener M, Senden N, Buurman W