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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?


To: Robert K. who wrote (14004)7/6/2000 7:49:12 AM
From: Oak Tree  Read Replies (1) | Respond to of 17367
 
In the case of LBP however, a little is good a lot is bad. The same is true, but little known, about TNF. Low doses of TNF are a very powerful growth factor, yes growth factor. Its so powerful, that it must have its own feedback loop, and becomes a very powerful killer if the dose increases to even low detectable levels.

By this argument, low levels of BPI might be bad and high levels good -- hence the need for 15x or higher. Even however if this is true, it supports my previous statements. This drug is hard to use safely and effectively, the moon and stars have to be in the correct orbit. This is not a robust reliable antimicrobial therapy.



To: Robert K. who wrote (14004)7/6/2000 12:57:16 PM
From: Bluegreen  Read Replies (1) | Respond to of 17367
 
A little review for newbies>>>>>>>>>>>>>"The science behind NEUPREX®, and the BPI platform for product development, are complementary to our recombinant and vaccines businesses," said Thomas Glanzmann, president, Hyland Immuno. "It serves as an excellent illustration of the strategic growth underway at Hyland Immuno as we diversify our biotechnology portfolio."
"We're pleased to have Baxter as our ally," said Jack Castello, chairman, president and CEO of XOMA. "They have excellent worldwide marketing and sales capabilities, particularly in the critical care and emergency hospital market. With Baxter's involvement, we believe we can maximize the value of NEUPREX® by aiming not only for meningococcemia but also for a wide variety of other medical indications."
"I am delighted about this relationship with XOMA," said Norbert Riedel, Ph.D., president of Hyland Immuno's Recombinant business. "NEUPREX® addresses an unmet medical need for a critically-ill patient population, and allows Baxter Hyland Immuno the opportunity to bring this product as quickly as possible to the patient and their families who so desperately need it."<<<<<<<<<<<<<<<<<<<<<<<<<



To: Robert K. who wrote (14004)7/6/2000 6:22:36 PM
From: Cacaito  Read Replies (1) | Respond to of 17367
 
Rk, your only contention is PLAIN WRONG!, just because some packages of blood has "up to 15 x bpi" does not mean all of the packs do, neither that there are many that are low or even very low.

Plus, that what the placebo group is all about, to get everything (even "unforeseen" bpi in packs of blood to be transfused) accounted for!

BPI DID NOT WORK!!! simple as that! your concoctions should be sent to xoma bax fda, not the board!