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To: Voltaire who wrote (25786)7/18/2000 12:50:35 PM
From: Voltaire  Respond to of 35685
 
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03/16/00- Updated 09:46 AM ET




March 16, 2000

Heart guard: Niacin, cholesterol drug
By Steve Sternberg, USA TODAY

ANAHEIM, Calif. - Coupling a cholesterol-lowering drug with high-dose niacin, a vitamin found in leafy vegetables, may sharply reduce heart-disease risk, research says.

Niacin does little in the trace amounts found in vegetables, but doctors have known since the 1950s that niacin in big doses can remedy cholesterol abnormalities in the blood - while sharply raising levels of HDL, the "good" cholesterol that protects against artery disease.

Doses big enough to achieve that effect, 200 to 500 milli grams, have major drawbacks. They can leave users flushed (with a red face and torso) or bring on a rash or liver damage.

But combining an extended-release form of niacin with the widely used cholesterol-lowering drug lovastatin dramatically improved blood cholesterol levels without severe side effects, researchers reported at the American College of Cardiology meeting here.

Prior studies showed that cholesterol-lowering drugs alone can markedly reduce blood levels of bad cholesterol, LDL, but they only raise HDL levels by about 10%. Adding Niacin solves that problem.

"Niacin is the most potent drug known for raising HDL," says lead investigator Moti Kashyap of the Veterans Affairs Healthcare System in Long Beach, Calif.

The new combination raised HDL levels by 41% after one year in a trial of 814 high-risk patients at 41 medical centers. The increase in HDL was 30% after 16 weeks, researchers say. The duo was named Niaspan by its manufacturer, Kos Pharmaceuticals of Miami Lakes, Fla. The combination proved safe, Kashyap says. Twenty-two percent of volunteers dropped out of the study because of flushing and other side effects.

"That's a very significant finding," says Adolph Hutter of Harvard Medical School, who adds that the combo represents an important option for people who need more help controlling their cholesterol



To: Voltaire who wrote (25786)7/18/2000 2:40:49 PM
From: Dr. David Gleitman  Respond to of 35685
 
Greetings V and all:

Regarding Selenium. It has been known for a while in certain circles that selenium has a beneficial effect for skin healing (wound care, psoriasis, etc...).

Just throwing my $0.02 in.

BTW, to all holders of BRCM. I made several "mistakes" is selling cc's. Sold the July 200's after the S&P 500 announcement where is shot up from the 140's to the 160's nearly a month ago. I bought some more BRCM @ 230 and sold cc's for the July 230's for a premium of 10, and bought back some of my July 200's and rolled them over to the July 250, which I later rolled up into the July 260's for a 6.25 premium. I broke my rule of looking at the maximum open interest (which is July 250), I didn't want my Leaps to be taken. Now here's a question for you. If I own the BRCM 2001 160 leaps and I write cc's against it and it is in the money during options expirtation, do I have to exercise my leap prematurely and buy the stock to give it up at the given stike price?

Answers would be appreicated?

Regards to all on the thread.

David