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Biotech / Medical : XOMA. Bull or Bear? -- Ignore unavailable to you. Want to Upgrade?

To: Robert K. who wrote (14179)	7/19/2000 10:33:06 PM
From: aknahow	Read Replies (1) \| Respond to of 17367

Robert, if you found it 4 months ago, you click a lot faster than I do. It was issued 30 May. United States Patent 6,069,126 Abruzzo , et al. May 30, 2000 Antifungal combination therapy Abstract There is described antifungal combination therapy comprising the use of known antifungal agents such as the azoles or polyenes in combination with a pneumocandin derivative antifungal agent. More particularly, the invention relates to antifungal combination therapy comprising the use of azoles such as fluconazole, voriconazole, itraconazole, ketoconazole, miconazole, ER 30346, SCH 56592; polyenes such as amphotericin B, nystatin or liposomal and lipid forms thereof such as Abelcet, AmBisome and Amphocil; purine or pyrimidine nucleotide inhibitors such as flucytosine; or polyoxins such as nikkomycins, in particular nikkomycin Z or other chitin inhibitors, elongation factor inhibitors such as sordarin and analogs thereof, mannan inhibitors such as predamycin, bactericidal/permeability-inducing (BPI) protein products such as XMP.97 or XMP.127 or complex carbohydrate antifungal agents such as CAN-296 in combination with a pneumocandin derivative as described herein. Inventors: Abruzzo; George K. (Clark, NJ); Bartizal; Kenneth F. (Somerset, NJ); Flattery; Amy M. (Sayreville, NJ) Assignee: Merck & Co., Inc. (Rahway, NJ)