To: Edward W. Richmond who wrote (1049 ) 10/6/2000 12:03:06 AM From: Ian@SI Read Replies (2) | Respond to of 1321 Ed, Afterhours spread for most NASDAQ traded companies is near meaningless. Re QLT Communications: They've now opened their earnings conference calls to the investing public; and media for that matter. In the last call, quite good guidance was given, including the companies expectations for a less aggressive ramp this Q; and the reasons why - both Doctors and patients like to take vacations during the summer; second treatment wouldn't be required in the very next Q; etc. So LeDink either ignored the guidance, didn't understand the guidance; or chose to deliberately misinform the public. For LeDink to do an inadequate spot survey, then to use that statistically invalid data to guess at revenues not for the current Q, not for the next Q, not even for Next Year; or event the Year after that, but for 3 and 4 years out,... Anybody stupid enough to get burned by that bull was probably going to be parted from his/her money anyway. Sample sizes were as small as 180 patients per retinal specialist. i.e. - it's conceivable that the poll covered not much more than 7200 patients at the 40 doctors; and probably much less than 100,000 patients Regardless, we still have 500,000 new cases of ARMD annually; and the applications for an expanded label; if you go back to the last Christine Charest of Nesbitt Burns analysis posted on this thread by Julian, you'll find accurate information which will give you a feel for how much everyone except LeDink is underestimating QLT's revenue growth. I expect QLT to double from its high within the next 18 months to 2 years; or to triple from current prices in that same time. I could be wrong. It might be much more than that. :-) Ian.