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To: Judith Williams who wrote (968)10/19/2000 7:26:48 PM
From: Clappy  Read Replies (1) | Respond to of 1115
 
Hi Biotech Lady,

Looks like CRA and LEXG may have made a bottom and could begin to climb back up.

We'll see...

Did you see CRA's mouse story?
How do you think LEXG's knockout mice will relate to this?
I thought they already had a lot of this type of information. Perhaps LEXG doesn't have the entire genome mapped? Just the important genes?

Anyhow, it sounds like CRA is way ahead of the government consortium again...

redherring.com

Mice trap cash for Celera
By Tom Davey
Redherring.com, October 18, 2000

The study of rodents has long played a role in
understanding human diseases and searching for cures.
Now, scientists are completing their mapping of the mouse
genome, which is very similar to the human genome. In the
future, rodent research should provide shortcuts in finding
parts of the human genome that play a role in specific
diseases.

Celera Genomics (NYSE: CRA) announced last week that it
has sequenced about 95 percent of the mouse genome,
using genetic sequences from three separate strains of
mice. Perhaps Celera's timing was a coincidence, but the
company once again appeared to upstage a public-private
consortium with this announcement. Just six days earlier,
the Mouse Sequencing Consortium, backed by SmithKline
Beecham (NYSE: SBH), Affymetrix (Nasdaq: AFFX), The
Wellcome Trust, and six of the National Institutes of
Health, disclosed it was investing $58 million in sequencing
the mouse genome over the next six months. Celera staged
a similar public relations coup earlier this year when it
announced its work on the human genome well before the
completion of a similar effort by the government.

Whereas Celera plans to make money by selling its mouse
genomic databases, the government consortium will publish
its own database on the Internet as a free service to
researchers. But because the consortium is using a mouse
strain that is different from the three Celera is using,
analysts believe drug companies and universities will want
both because they'll be complementary.

So far, the bulk of Celera's revenues come from licensing its
databases and related consulting services. For its fiscal
year ending June 30, Celera lost $93 million on $43 million in
revenues.

THE BULLS
Most of the analysts who follow the stock are unconcerned
with the high growth costs and are optimistic about the
future. Winton Gibbons, an analyst for William Blair &
Company, says that when he started following Celera last
November, he predicted $65 million in revenue for the fiscal
year ending in June 2001. "The company has executed
beyond the best-case scenario," he says. "Now, we think it
should do more than $90 million in the current fiscal year."

Celera had better grow by at least that much to help
justify its $3.6 billion market value. Mr. Gibbons figures it
will. Ten years out, he predicts Celera will be raking in
somewhere between $1.4 billion and $4 billion in revenue
and will command a market value at that time of $15 billion
to $30 billion. Ironically, the stock peaked at that futuristic
value back in March and has since been in the doldrums,
now trading at about one-fifth of its 52-week high.

Mr. Gibbons says his figures might be conservative and
notes that by 2010 the company should have new revenue
streams such as percentage royalties on future drugs from
pharmaceutical companies that buy the database. But
compared with the many fast-growing companies in other
industries that are trading at relatively puny revenue
multiples, why would you want to bank on anything ten
years out unless you're buying at dirt-cheap prices?

MORE DOWNSIDE?
Some analysts and holders who like the company think
Celera may drop a bit further before it bottoms out. "A
whale of a lot of funds have lost money on Celera," says
Lissa Morgenthaler, portfolio manager for the Monterey
Murphy New World Biotechnology Fund. Because the fiscal
year for mutual funds ends November 30, she explains,
most funds will sell losing stocks by late October to offset
gains for tax purposes. Therefore, she expects Celera,
currently trading at $59, to dip to $50 or less before it
stages a rebound.

Coming up with an accurate value, however, is sheer
witchcraft. "You can't do a discounted cash-flow analysis
on Celera," says another analyst who loves the stock but
asked not to be named. "People are much more concerned
about subscriber growth right now. For a company with a
lot of hype like Celera, you can figure people will bid up the
multiple on it more than others."

Doesn't that sound exactly like what some analysts were
saying about dot-com retailers a year ago? Celera officials
were unavailable to comment for this story.



To: Judith Williams who wrote (968)10/19/2000 7:32:05 PM
From: Didi  Respond to of 1115
 
Hi Judy,

So happy to hear from you.

Always welcome, my friend.

Isn't the tech roller coaster fun?

Did you see the video version of Greenspan's speech? Full text below.

washingtonpost.com

Take care.

always,
di
-------------------------------------------------------------------------------------------------------

washingtonpost.com

>>> Greenspan Keeping an Eye on Oil Prices

By John M. Berry
Washington Post Staff Writer
Thursday , October 19, 2000

Federal Reserve Chairman Alan Greenspan said this morning that world oil prices are likely to fall from their recent highs and that the oil price spike has done little damage to the U.S. economy.

In an upbeat speech at The Cato Institute's annual monetary conference here, Greenspan also said there is no "credible evidence" that the acceleration of productivity growth, which has been spurred by technological advances in recent years, has come to an end.

The continuing gain in productivity – the amount of goods and services produced for each hour worked – has allowed firms to pay higher wages without passing those costs on to their customers and "has been essential to containing price increases," the Fed chairman said.

Touching on a key issue in the current presidential campaign, Greenspan said the big swing in the federal budget from large deficits in the early 1990's to growing surpluses most recently "has helped fill the pool of saving that has fed productivity-enhancing and cost-reducing capital formation." The earlier "outsized federal budget deficit . . . was absorbing an inordinate share of our national saving," he said.

Vice President Gore, the Democratic presidential nominee, frequently makes this same point about federal finances in his campaign appearances while attacking his opponent, Republican Gov. George W. Bush of Texas, for proposing a broad tax cut that would reduce future budget surpluses by $1.6 trillion over the next decade.

However, Gore has also proposed a series of smaller tax cuts that would reduce the surpluses by about $500 billion over the same period and has urged spending increases for a variety of programs that also would eat into the surplus.

"The mounting fiscal surpluses have been an important source of national saving, muting upward pressures on interest rates at a time of strong demand for private credit," Greenspan explained. "By keeping the cost of capital lower than it otherwise would have been, the surpluses have contributed to [greater capital investments] and faster growth of productivity."

Then with a nod to the campaign promises and the large increase in the fiscal 2001 budget now pending in Congress, he added, "But I believe most of us harbor doubts about whether the dynamics of the political process, some of which have been on display in the current budgetary deliberations, will allow the surpluses to continue to grow."

Greenspan's comments on the outlook for oil prices and how their increase has affected the economy were the most detailed he has ever given.

After noting that the U.S. economy uses oil much less intensively than it did in the 1970s when oil price spikes did great damage, the Fed chairman said it "still has the potential to alter the forces governing economic growth in the United States."

"To date, the spillover from the surge in oil prices has been modest," he said. "Any effect on inflation expectations . . . has been virtually nil. Moreover, despite some slowing that likely has been related in part to the bite from the so-called 'oil tax' on household incomes, the growth of consumer spending has remained firm. But policymakers will need to be on the alert for oil-driven, indeed energy-driven, risks to our expansion."

Greenspan said oil prices likely will fall because they currently are far above the cost of producing crude oil even from the most expensive oil fields in operation. New technological advances have "more than doubled the drilling success rate for new field wildcat wells during the past decade . . . [and] newer recovery techniques reportedly have raised the proportion of oil reserves eventually brought to the surface from a third to nearly a half in recent decades," he said.

While prices for oil currently available to refiners "have soared and plunged," the price per barrel in futures contracts calling for oil to be delivered six years down the road "generally moved lower over the past decade," Greenspan said. That six-year time span is long enough for companies "to seek, discover, drill and lift oil," he said.

"The most distant futures prices fell from a bit more than $20 per barrel just before the Gulf War [in 1990] to $17 to $18 a barrel a year ago. The current six-year contract has risen over the past year to about $21 per barrel. Arguably, however, this rise is related less to technology and the structure of underlying marginal costs and more to concerns about how quickly new practices will be exploited to expand the Organization of Petroleum Exporting Countries' productivity capacity," Greenspan said.

In the short run, prices soared because of very low worldwide oil inventories. But OPEC has raised production and it now is running nearly 1.5 million barrels a day higher than seasonally adjusted consumption, the Fed chairman said. That means inventories are being rebuilt but "are not yet back to normal levels." When they are, "it would certainly seem that . . . spot prices would shortly be under significant downward pressure," he said.

However, he cautioned, recent events in the Middle East, including new violence in Israel and the terrorist attack on a U.S. destroyer in Yemen, have raised additional uncertainties in oil buyers' minds about the future availability of supplies. That has caused some to try to build up their inventories even more, "which has helped keep prices high," he said.

Analysts said the speech, taken as a whole, suggested that Greenspan will not be seeking any change in interest rates when Fed policymakers meet Nov. 15. On the other hand, given some of the concerns he did mention, it is likely that he still regards the risk that inflation will get worse as outweighing the risk that economic growth will slow too much, the analysts said.

© 2000 The Washington Post <<<